6PIK
 
 | | Tetrameric cryo-EM ArnA | | 分子名称: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | 著者 | Yang, M, Gehring, K. | | 登録日 | 2019-06-26 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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6PIH
 | | Hexameric ArnA cryo-EM structure | | 分子名称: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | 著者 | Yang, M, Gehring, K. | | 登録日 | 2019-06-26 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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2VFX
 | | Structure of the Symmetric Mad2 Dimer | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | | 著者 | Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. | | 登録日 | 2007-11-05 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
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2UXN
 | | Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | | 分子名称: | CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H. | | 登録日 | 2007-03-28 | | 公開日 | 2007-05-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
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2UXX
 | | Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct | | 分子名称: | CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ... | | 著者 | Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H. | | 登録日 | 2007-03-30 | | 公開日 | 2007-08-21 | | 最終更新日 | 2019-02-06 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
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2IW5
 | | Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase | | 分子名称: | AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H. | | 登録日 | 2006-06-26 | | 公開日 | 2006-08-09 | | 最終更新日 | 2019-02-06 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
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4HY6
 | | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1 | | 分子名称: | 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one, Heat shock protein HSP 90-alpha | | 著者 | Yang, M, Li, J, He, J.H. | | 登録日 | 2012-11-13 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | | 主引用文献 | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
to be published
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2H2N
 | | Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | 分子名称: | ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | 著者 | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | 登録日 | 2006-05-19 | | 公開日 | 2006-07-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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2H2U
 | | Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | 分子名称: | CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | 著者 | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | 登録日 | 2006-05-19 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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7YDW
 | | Crystal structure of the MPND-DNA complex | | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MPN domain-containing protein | | 著者 | Yang, M, Chen, Z. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
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7YDT
 | | Crystal structure of mouse MPND | | 分子名称: | MPN domain containing protein | | 著者 | Yang, M, Chen, Z. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.055 Å) | | 主引用文献 | Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
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4W78
 | | Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis | | 分子名称: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | | 登録日 | 2014-08-21 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.541 Å) | | 主引用文献 | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
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4WNB
 | | Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis bound to 3-OPC-CoA | | 分子名称: | 3-oxo-4-pregnene-20-carboxyl-Coenzyme A, CADMIUM ION, CALCIUM ION, ... | | 著者 | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | | 登録日 | 2014-10-11 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
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5I5O
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5I5N
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4X28
 | | Crystal structure of the ChsE4-ChsE5 complex from Mycobacterium tuberculosis | | 分子名称: | Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | | 著者 | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | | 登録日 | 2014-11-26 | | 公開日 | 2015-02-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
Acs Infect Dis., 1, 2015
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4IKG
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4NQJ
 | | Structure of coiled-coil domain | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | | 著者 | Yang, M, Li, Y. | | 登録日 | 2013-11-25 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | | 主引用文献 | Structural insights into the TRIM family of ubiquitin E3 ligases.
Cell Res., 24, 2014
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5WY5
 | | Crystal structure of MAGEG1 and NSE1 complex | | 分子名称: | MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ... | | 著者 | Yang, M, Gao, J. | | 登録日 | 2017-01-11 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
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3T9N
 | | Crystal structure of a membrane protein | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | | 著者 | Yang, M, Zhang, X, Ge, J, Wang, J. | | 登録日 | 2011-08-03 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.456 Å) | | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
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4PSX
 | | Crystal structure of histone acetyltransferase complex | | 分子名称: | COENZYME A, Histone H3, Histone H4, ... | | 著者 | Yang, M, Li, Y. | | 登録日 | 2014-03-08 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.509 Å) | | 主引用文献 | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4PSW
 | | Crystal structure of histone acetyltransferase complex | | 分子名称: | COENZYME A, Histone H4 type VIII, Histone acetyltransferase type B catalytic subunit, ... | | 著者 | Yang, M, Li, Y. | | 登録日 | 2014-03-08 | | 公開日 | 2014-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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5YE2
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5YE1
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5YE5
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