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6PIH

Hexameric ArnA cryo-EM structure

Summary for 6PIH
Entry DOI10.2210/pdb6pih/pdb
EMDB information0456
DescriptorBifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase (2 entities in total)
Functional Keywordspolymyxin resistance, hexamer, tetramer, antibiotic
Biological sourceEscherichia coli DH5[alpha]
More
Total number of polymer chains12
Total formula weight436650.01
Authors
Yang, M.,Gehring, K. (deposition date: 2019-06-26, release date: 2019-07-31, Last modification date: 2024-03-13)
Primary citationYang, M.,Chen, Y.S.,Ichikawa, M.,Calles-Garcia, D.,Basu, K.,Fakih, R.,Bui, K.H.,Gehring, K.
Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208:43-50, 2019
Cited by
PubMed: 31344437
DOI: 10.1016/j.jsb.2019.07.009
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (6.6 Å)
Structure validation

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