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2IW5

Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase

Summary for 2IW5
Entry DOI10.2210/pdb2iw5/pdb
Related2COM
DescriptorLYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
Functional Keywordsoxidoreductase-transcription regulator complex, oxidoreductase-repressor complex, histone demethylase, fad, lsd1, corest, repressor, transcription regulation, host-virus interaction, chromatin demethylation, nuclear protein, phosphorylation, chromatin regulator, nucleosomes, transcription, oxidoreductase, oxidoreductase/transcription regulator
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains2
Total formula weight101646.65
Authors
Yang, M.,Gocke, C.B.,Luo, X.,Borek, D.,Tomchick, D.R.,Machius, M.,Otwinowski, Z.,Yu, H. (deposition date: 2006-06-26, release date: 2006-08-09, Last modification date: 2019-02-06)
Primary citationYang, M.,Gocke, C.B.,Luo, X.,Borek, D.,Tomchick, D.R.,Machius, M.,Otwinowski, Z.,Yu, H.
Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23:377-, 2006
Cited by
PubMed: 16885027
DOI: 10.1016/J.MOLCEL.2006.07.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.57 Å)
Structure validation

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