4HY6

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1

Summary for 4HY6

• Entry DOI: 10.2210/pdb4hy6/pdb
• Descriptor: Heat shock protein HSP 90-alpha, 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one (3 entities in total)
• Functional Keywords: atp binding, molecularchaperone, inhibitor, rossmann fold, molecular chaperone, atp hydrolysis, chaperone-chaperone inhibitor complex, chaperone/chaperone inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P07900
• Total number of polymer chains: 1
• Total formula weight: 25888.97

Authors

Yang, M.,Li, J.,He, J.H. (deposition date: 2012-11-13, release date: 2013-05-15, Last modification date: 2023-11-08)

• Primary citation: Yang, M.,Li, J.,He, J.H.; Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1; to be published,

Experimental method

X-RAY DIFFRACTION (1.649 Å)