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4HY6

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Heat shock protein HSP 90-alphapolymer22825656.81UniProt (P07900)
Pfam (PF13589)
Homo sapiens (human)Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38
2B
(A)
6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-onenon-polymer232.21Chemie (FJ1)
3C
(A)
waterwater18.0102Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight25656.8
Non-Polymers*Number of molecules1
Total formula weight232.2
All*Total formula weight25889.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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