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2VFX

Structure of the Symmetric Mad2 Dimer

Summary for 2VFX
Entry DOI10.2210/pdb2vfx/pdb
Related1DUJ 1GO4 1KLQ 1S2H 2V64
DescriptorMITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywordsmad2, mad1, cdc2, nucleus, mitosis, anaphase, cell cycle, cell division, spindle checkpoint, anaphase-promoting complex
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains12
Total formula weight288684.83
Authors
Yang, M.,Li, B.,Liu, C.-J.,Tomchick, D.R.,Machius, M.,Rizo, J.,Yu, H.,Luo, X. (deposition date: 2007-11-05, release date: 2008-03-18, Last modification date: 2023-12-13)
Primary citationYang, M.,Li, B.,Liu, C.-J.,Tomchick, D.R.,Machius, M.,Rizo, J.,Yu, H.,Luo, X.
Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6:E50-, 2008
Cited by
PubMed: 18318601
DOI: 10.1371/JOURNAL.PBIO.0060050
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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