4Q2Z
| Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate | 分子名称: | Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody | 著者 | Navis, M, Tran, K, Bale, S, Phad, G, Guenaga, J, Wilson, R, Soldemo, M, McKee, K, Sundling, C, Mascola, J, Li, Y, Wyatt, R.T, Hedestam, G.B.K. | 登録日 | 2014-04-10 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization. Plos Pathog., 10, 2014
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4KTE
| Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE148, from non-human primate | 分子名称: | GE148 Heavy Chain Fab, GE148 Light Chain Fab, GLYCEROL, ... | 著者 | Poulsen, C, Tran, K, Stanfield, R, Wyatt, R.T. | 登録日 | 2013-05-20 | 公開日 | 2014-02-05 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
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4KTD
| Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate | 分子名称: | GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ... | 著者 | Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T. | 登録日 | 2013-05-20 | 公開日 | 2014-02-05 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
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4TOY
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6XLZ
| Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide | 分子名称: | (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ... | 著者 | Aljedani, S, Rodarte, J, Liban, T, Pancera, M. | 登録日 | 2020-06-29 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6XSN
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5EWI
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6P62
| HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 NFL TD+, ... | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2019-05-31 | 公開日 | 2019-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
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6PEH
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6P65
| HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2019-05-31 | 公開日 | 2019-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
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5VGJ
| Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90, bound to a scaffolded WITO V1V2 domain | 分子名称: | 1FD6-V1V2-WITO, 2-acetamido-2-deoxy-beta-D-glucopyranose, VRC38.01 Fab Heavy Chain, ... | 著者 | Gorman, J, Li, J, Kwong, P.D. | 登録日 | 2017-04-11 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.456 Å) | 主引用文献 | Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity, 46, 2017
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6AVN
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6B0N
| Crystal structure of the cleavage-independent prefusion HIV Env glycoprotein trimer of the clade A BG505 isolate (NFL construct) in complex with Fabs PGT122 and PGV19 at 3.39 A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp140, ... | 著者 | Sarkar, A, Irimia, A, Wilson, I.A. | 登録日 | 2017-09-14 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nat Commun, 9, 2018
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6MAR
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6U3Z
| Structure of VD20_5A4 Fab | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Dionne, G, Shapiro, L. | 登録日 | 2019-08-22 | 公開日 | 2019-11-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99002314 Å) | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
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6U9U
| Structure of GM9_TH8seq732127 FAB | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | 著者 | Singh, S, Liban, T.J, Pancera, M. | 登録日 | 2019-09-09 | 公開日 | 2019-11-06 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
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4L8I
| Crystal structure of RSV epitope scaffold FFL_005 | 分子名称: | RSV epitope scaffold FFL_005 | 著者 | Jardine, J, Correnti, C, Holmes, M.A, Strong, R.K, Schief, W.R. | 登録日 | 2013-06-17 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Proof of principle for epitope-focused vaccine design. Nature, 507, 2014
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6VJN
| Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide | 分子名称: | D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ... | 著者 | Singh, S, Liban, T.J, Pancera, M. | 登録日 | 2020-01-16 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6WAS
| Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold | 分子名称: | 1FD6 16055 V1V2 scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, GN1_PA8 Fab Heavy chain, ... | 著者 | Singh, S, Liban, T.J, Pancera, M. | 登録日 | 2020-03-26 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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4N9G
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6WIT
| Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold | 分子名称: | 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ... | 著者 | Liban, T, Aljedani, S, Rodarte, J, Pancera, M. | 登録日 | 2020-04-10 | 公開日 | 2021-04-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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5CD3
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5CD5
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4JLR
| Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab | 分子名称: | Motavizumab Fab heavy chain, Motavizumab Fab light chain, PENTAETHYLENE GLYCOL, ... | 著者 | Rupert, P.B, Correia, B, Schief, W, Strong, R.K. | 登録日 | 2013-03-12 | 公開日 | 2014-02-05 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Proof of principle for epitope-focused vaccine design. Nature, 507, 2014
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6OAF
| Sudan virus nucleoprotein core domain in complex with VP35 chaperoning peptide | 分子名称: | Polymerase cofactor VP35,Nucleoprotein | 著者 | Landeras-Bueno, S, Oda, S, Norris, M.J, Li Salie, Z, Ollmann Saphire, E. | 登録日 | 2019-03-15 | 公開日 | 2019-08-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment. Mbio, 10, 2019
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