4KTD
Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate
Summary for 4KTD
Entry DOI | 10.2210/pdb4ktd/pdb |
Related | 4KTE |
Descriptor | GE136 Heavy Chain Fab, GE136 Light Chain Fab, SULFATE ION, ... (5 entities in total) |
Functional Keywords | antibody affinity, antibody specificity, vaccine elicited antibodies, fab fragment, aids vaccines, immune system |
Biological source | Macaca mulatta (rhesus macaque) More |
Total number of polymer chains | 2 |
Total formula weight | 48477.89 |
Authors | Poulsen, C.,Tran, K.,Standfield, R.,Wyatt, R.T. (deposition date: 2013-05-20, release date: 2014-02-05, Last modification date: 2017-11-15) |
Primary citation | Tran, K.,Poulsen, C.,Guenaga, J.,de Val Alda, N.,Wilson, R.,Sundling, C.,Li, Y.,Stanfield, R.L.,Wilson, I.A.,Ward, A.B.,Karlsson Hedestam, G.B.,Wyatt, R.T. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111:E738-E747, 2014 Cited by PubMed: 24550318DOI: 10.1073/pnas.1319512111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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