4L8I

Crystal structure of RSV epitope scaffold FFL_005

Summary for 4L8I

• Entry DOI: 10.2210/pdb4l8i/pdb
• Descriptor: RSV epitope scaffold FFL_005 (2 entities in total)
• Functional Keywords: three-helix bundle, immune system
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 27419.51

Authors

Jardine, J.,Correnti, C.,Holmes, M.A.,Strong, R.K.,Schief, W.R. (deposition date: 2013-06-17, release date: 2014-02-12, Last modification date: 2024-02-28)

• Primary citation: Correia, B.E.,Bates, J.T.,Loomis, R.J.,Baneyx, G.,Carrico, C.,Jardine, J.G.,Rupert, P.,Correnti, C.,Kalyuzhniy, O.,Vittal, V.,Connell, M.J.,Stevens, E.,Schroeter, A.,Chen, M.,Macpherson, S.,Serra, A.M.,Adachi, Y.,Holmes, M.A.,Li, Y.,Klevit, R.E.,Graham, B.S.,Wyatt, R.T.,Baker, D.,Strong, R.K.,Crowe, J.E.,Johnson, P.R.,Schief, W.R.; Proof of principle for epitope-focused vaccine design.; Nature, 507:201-206, 2014; PubMed: 24499818; DOI: 10.1038/nature12966

Experimental method

X-RAY DIFFRACTION (2 Å)