5CD5
Crystal structure of an immature VRC01-class antibody DRVIA7 from a Chinese donor bound to clade A/E HIV-1 gp120 core
Summary for 5CD5
Entry DOI | 10.2210/pdb5cd5/pdb |
Related | 5CD3 |
Descriptor | 93TH057 HIV-1 gp120 core, DRVIA7 Fab Heavy Chain, DRVIA7 Fab Light Chain, ... (7 entities in total) |
Functional Keywords | vrc01, gp120, hiv-1, antibody, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 89978.61 |
Authors | Kong, L.,Wilson, I.A. (deposition date: 2015-07-03, release date: 2016-04-06, Last modification date: 2020-07-29) |
Primary citation | Kong, L.,Ju, B.,Chen, Y.,He, L.,Ren, L.,Liu, J.,Hong, K.,Su, B.,Wang, Z.,Ozorowski, G.,Ji, X.,Hua, Y.,Chen, Y.,Deller, M.C.,Hao, Y.,Feng, Y.,Garces, F.,Wilson, R.,Dai, K.,O'Dell, S.,McKee, K.,Mascola, J.R.,Ward, A.B.,Wyatt, R.T.,Li, Y.,Wilson, I.A.,Zhu, J.,Shao, Y. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity, 44:939-950, 2016 Cited by PubMed: 27067056DOI: 10.1016/j.immuni.2016.03.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.396 Å) |
Structure validation
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