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6WAS

Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold

Summary for 6WAS
Entry DOI10.2210/pdb6was/pdb
DescriptorGN1_PA8 Fab Heavy chain, GN1_PA8 Fab Light chain, 1FD6 16055 V1V2 scaffold, ... (5 entities in total)
Functional Keywordsfragment binding antigen and peptide complex, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains6
Total formula weight129539.15
Authors
Singh, S.,Liban, T.J.,Pancera, M. (deposition date: 2020-03-26, release date: 2021-03-31, Last modification date: 2023-10-18)
Primary citationAljedani, S.S.,Liban, T.J.,Tran, K.,Phad, G.,Singh, S.,Dubrovskaya, V.,Pushparaj, P.,Martinez-Murillo, P.,Rodarte, J.,Mileant, A.,Mangala Prasad, V.,Kinzelman, R.,O'Dell, S.,Mascola, J.R.,Lee, K.K.,Karlsson Hedestam, G.B.,Wyatt, R.T.,Pancera, M.
Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17:e1009543-e1009543, 2021
Cited by
PubMed: 34559844
DOI: 10.1371/journal.ppat.1009543
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.904 Å)
Structure validation

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