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STRUCTURE OF A TETRAHEDRAL TRANSITION STATE COMPLEX OF ALPHA-CHYMOTRYPSIN AT 1.8-ANGSTROMS RESOLUTION
分子名称:	ALPHA-CHYMOTRYPSIN A, PHENYLETHANE BORONIC ACID
著者	Tulinsky, A, Blevins, R.A.
登録日	1987-02-06
公開日	1987-04-16
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution. J.Biol.Chem., 262, 1987

2PK4

THE REFINED STRUCTURE OF THE EPSILON-AMINOCAPROIC ACID COMPLEX OF HUMAN PLASMINOGEN KRINGLE
分子名称:	6-AMINOHEXANOIC ACID, HUMAN PLASMINOGEN KRINGLE 4
著者	Tulinsky, A, Wu, T.-P.
登録日	1991-07-18
公開日	1993-10-31
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4. Biochemistry, 30, 1991

4HTC

THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者	Tulinsky, A, Rydel, T.J, Bode, W, Huber, R.
登録日	1993-06-25
公開日	1994-01-31
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Refined structure of the hirudin-thrombin complex. J.Mol.Biol., 221, 1991

3HAT

ACTIVE SITE MIMETIC INHIBITION OF THROMBIN
分子名称:	FPAM (FIBRINOPEPTIDE A MIMIC), Hirudin variant-2, Thrombin heavy chain, ...
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-10-16
公開日	1995-02-27
最終更新日	2024-04-24
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Active-site mimetic inhibition of thrombin. Acta Crystallogr.,Sect.D, 51, 1995

5HPG

STRUCTURE AND LIGAND DETERMINANTS OF THE RECOMBINANT KRINGLE 5 DOMAIN OF HUMAN PLASMINOGEN
分子名称:	PLASMINOGEN
著者	Tulinsky, A, Mochalkin, I, Castellino, F.J.
登録日	1997-09-19
公開日	1998-03-25
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (1.66 Å)
主引用文献	Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen. Biochemistry, 37, 1998

2HPQ

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
著者	Tulinsky, A, Padmanabhan, K.
登録日	1993-04-28
公開日	1994-01-31
最終更新日	2013-02-27
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin. Biochemistry, 32, 1993

2HPP

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
分子名称:	ALPHA-THROMBIN HEAVY CHAIN, ALPHA-THROMBIN LIGHT CHAIN, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
著者	Tulinsky, A, Padmanabhan, K.
登録日	1993-04-28
公開日	1994-01-31
最終更新日	2013-02-27
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin. Biochemistry, 32, 1993

2SPT

DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, PROTHROMBIN, STRONTIUM ION
著者	Tulinsky, A.
登録日	1994-02-01
公開日	1994-05-31
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1. Biochemistry, 33, 1994

2HGT

STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), Hirulog
著者	Tulinsky, A, Carperos, V.
登録日	1991-06-03
公開日	1994-01-31
最終更新日	2016-11-09
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. J.Mol.Biol., 221, 1991

2HNT

CRYSTALLOGRAPHIC STRUCTURE OF HUMAN GAMMA-THROMBIN
分子名称:	GAMMA-THROMBIN
著者	Tulinsky, A.
登録日	1994-08-23
公開日	1994-11-30
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystallographic structure of human gamma-thrombin. J.Biol.Chem., 269, 1994

3HTC

THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2
著者	Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W.
登録日	1993-06-11
公開日	1994-01-31
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990

1PK4

CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 4 REFINED AT 1.9-ANGSTROMS RESOLUTION
分子名称:	PLASMINOGEN KRINGLE 4, SULFATE ION
著者	Tulinsky, A, Mulichak, A.M.
登録日	1991-07-18
公開日	1993-10-31
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution. Biochemistry, 30, 1991

1DIT

COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN
分子名称:	ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995
著者	Tulinsky, A, Krishnan, R.
登録日	1995-07-20
公開日	1996-06-10
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic. Protein Sci., 5, 1996

1KGA

STRUCTURE OF 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE AT 2.8 ANGSTROMS RESOLUTION
分子名称:	2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE
著者	Tulinsky, A.
登録日	1978-08-21
公開日	1978-10-13
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (3.5 Å)
主引用文献	Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase at 2 . 8 A resolution. J.Mol.Biol., 162, 1982

1HXF

HUMAN THROMBIN COMPLEX WITH HIRUDIN VARIANT
分子名称:	HIRUDIN VARIANT, THROMBIN
著者	Tulinsky, A, Zhang, E.
登録日	1996-09-09
公開日	1997-01-27
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	The molecular environment of the Na+ binding site of thrombin. Biophys.Chem., 63, 1997

1HAH

THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者	Tulinsky, A, Vijayalakshmi, J.
登録日	1994-06-27
公開日	1994-12-20
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci., 3, 1994

1HAG

THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUGEN, PRETHROMBIN 2
著者	Tulinsky, A, Vijayalakshmi, J.
登録日	1994-06-27
公開日	1994-12-20
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci., 3, 1994

1CEA

THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID)
分子名称:	6-AMINOHEXANOIC ACID, PLASMINOGEN
著者	Tulinsky, A, Mathews, I.I.
登録日	1995-12-03
公開日	1996-04-03
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.06 Å)
主引用文献	Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid. Biochemistry, 35, 1996

1CEB

THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID)
分子名称:	PLASMINOGEN, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
著者	Tulinsky, A, Mathews, I.I.
登録日	1995-12-03
公開日	1996-04-03
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.07 Å)
主引用文献	Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid. Biochemistry, 35, 1996

1FPC

ACTIVE SITE MIMETIC INHIBITION OF THROMBIN
分子名称:	Hirudin, amino{[(4S)-4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)-5-(4-ethylpiperidin-1-yl)-5-oxopentyl]amino}methaniminium, thrombin
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-10-16
公開日	1995-02-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Active-site mimetic inhibition of thrombin. Acta Crystallogr.,Sect.D, 51, 1995

1NRS

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ...
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-01-18
公開日	1994-05-31
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

1NRR

Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes
分子名称:	D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Proteinase-activated receptor 1, Thrombin heavy chain, ...
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-01-18
公開日	1994-05-31
最終更新日	2013-02-27
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

1NRN

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRS
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-01-18
公開日	1994-05-31
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

1NRO

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRP
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-01-18
公開日	1994-05-31
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

1NRP

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NR'S
著者	Tulinsky, A, Mathews, I.I.
登録日	1994-01-18
公開日	1994-05-31
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

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