1HAG

THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN

Summary for 1HAG

DescriptorPRETHROMBIN 2, HIRUGEN, N-ACETYL-D-GLUCOSAMINE, ... (4 entities in total)
Functional Keywordscomplex(serine proteinase-inhibitor), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total molecular weight35443.34
Authors
Tulinsky, A.,Vijayalakshmi, J. (deposition date: 1994-06-27, release date: 1994-12-20, Last modification date: 2019-08-14)
Primary citation
Vijayalakshmi, J.,Padmanabhan, K.P.,Mann, K.G.,Tulinsky, A.
The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3:2254-2271, 1994
PubMed: 7756983 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers61 3.7% 21.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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