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4PWQ
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BU of 4pwq by Molmil
HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEIN
Descriptor: Amyloid beta A4 protein
Authors:Hoefgen, S, Dahms, S.O, Than, M.E.
Deposit date:2014-03-21
Release date:2015-02-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain.
J.Mol.Biol., 427, 2015
3UMK
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BU of 3umk by Molmil
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with copper
Descriptor: ACETATE ION, Amyloid beta A4 protein, CADMIUM ION, ...
Authors:Dahms, S.O, Konnig, I, Roeser, D, Guhrs, K.H, Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
3UMH
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BU of 3umh by Molmil
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with cadmium
Descriptor: ACETATE ION, Amyloid beta A4 protein, CADMIUM ION
Authors:Dahms, S.O, Konnig, I, Roeser, D, Guhrs, K.H, Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
3UMI
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BU of 3umi by Molmil
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with zinc
Descriptor: ACETATE ION, Amyloid beta A4 protein, CADMIUM ION, ...
Authors:Dahms, S.O, Konnig, I, Roeser, D, Guhrs, K.H, Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
3QO4
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BU of 3qo4 by Molmil
The Crystal Structure of Death Receptor 6
Descriptor: ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21
Authors:Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E.
Deposit date:2011-02-09
Release date:2011-05-18
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
1EHK
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BU of 1ehk by Molmil
CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS
Descriptor: BA3-TYPE CYTOCHROME-C OXIDASE, COPPER (II) ION, DINUCLEAR COPPER ION, ...
Authors:Soulimane, T, Buse, G, Bourenkov, G.P, Bartunik, H.D, Huber, R, Than, M.E.
Deposit date:2000-02-21
Release date:2001-02-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus.
EMBO J., 19, 2000
2F9P
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BU of 2f9p by Molmil
Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant D216G in Complex with Leupeptin
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leupeptin, ...
Authors:Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
2F9N
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BU of 2f9n by Molmil
Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leupeptin, ...
Authors:Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
2F9O
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BU of 2f9o by Molmil
Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant D216G
Descriptor: Tryptase alpha-1, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
1P8J
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BU of 1p8j by Molmil
CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ...
Authors:Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
6HZA
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BU of 6hza by Molmil
X-ray structure of furin in complex with the cyclic peptide c[glutaryl-Arg-Arg-Lys]-Arg-4-Amba
Descriptor: ARG-ARG-LYS-ARG-00S, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-10-23
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HLB
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BU of 6hlb by Molmil
X-ray structure of furin in complex with the cyclic peptide c[succinyl-Phe-2-Nal-(Arg)4-Lys]-Arg-4-Amba
Descriptor: CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Dahms, S.O.
Deposit date:2018-09-11
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HLE
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BU of 6hle by Molmil
X-ray structure of furin in complex with the P6-P2-cyclized peptide H-Lys-Arg-Arg-Tle-Lys-4-Amba
Descriptor: 3-[4-(3-oxidanylidenepropyl)piperazin-1-yl]propanal, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-09-11
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HZD
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BU of 6hzd by Molmil
X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-Arg-Arg-Arg-Lys]-Arg-4-Amba
Descriptor: ARG-ARG-ARG-LYS-ARG-00S, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-10-23
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HZC
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BU of 6hzc by Molmil
X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-BVK-Lys-Arg-Arg-Tle-Lys]-4-Amba
Descriptor: 2-[4-(aminomethyl)phenyl]ethanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-10-23
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HZB
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BU of 6hzb by Molmil
X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-Arg-Arg-Lys]-Lys-4-Amba
Descriptor: ARG-ARG-LYS-LYS-00S, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-10-23
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
6HLD
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BU of 6hld by Molmil
X-ray structure of furin in complex with the cyclic peptide c[succinyl-Phe-2-Nal-(Arg)3-Lys]-Lys-4-Amba
Descriptor: ALN-ARG-ARG-ARG-SLL-LYS-00S, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O.
Deposit date:2018-09-11
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Chemmedchem, 14, 2019
2NAP
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BU of 2nap by Molmil
DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Dias, J.M, Than, M, Humm, A, Huber, R, Bourenkov, G, Bartunik, H, Bursakov, S, Calvete, J, Caldeira, J, Carneiro, C, Moura, J, Moura, I, Romao, M.J.
Deposit date:1998-09-18
Release date:1999-09-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the first dissimilatory nitrate reductase at 1.9 A solved by MAD methods.
Structure Fold.Des., 7, 1999
2GV6
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BU of 2gv6 by Molmil
Crystal Structure of Matriptase with Inhibitor CJ-730
Descriptor: (S)-3-(3-(4-(2-GUANIDINOETHYL)PIPERIDIN-1-YL)-2-(NAPHTHALENE-2-SULFONAMIDO)-3-OXOPROPYL)BENZIMIDAMIDE, Suppressor of tumorigenicity 14
Authors:Bode, W.
Deposit date:2006-05-02
Release date:2006-06-06
Last modified:2021-06-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase.
J.Med.Chem., 49, 2006
2GV7
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BU of 2gv7 by Molmil
Structure of Matriptase in Complex with Inhibitor CJ-672
Descriptor: (S)-4-(4-(3-(3-CARBAMIMIDOYLPHENYL)-2-(2,4,6-TRIISOPROPYLPHENYLSULFONAMIDO)PROPANOYL)PIPERAZINE-1-CARBONYL)PIPERIDINE-1-CARBOXIMIDAMIDE, Suppressor of tumorigenicity 14
Authors:Bode, W.
Deposit date:2006-05-02
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase.
J.Med.Chem., 49, 2006
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