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2F9N

Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin

Summary for 2F9N
Entry DOI10.2210/pdb2f9n/pdb
Related2F9O 2F9P
Related PRD IDPRD_000216
Descriptoralpha I tryptase, Leupeptin, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsserine proteinase, leupeptin, trypsin-like, difucosylation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains8
Total formula weight114593.14
Authors
Rohr, K.B.,Selwood, T.,Marquardt, U.,Huber, R.,Schechter, N.M.,Bode, W.,Than, M.E. (deposition date: 2005-12-06, release date: 2006-01-31, Last modification date: 2023-08-30)
Primary citationRohr, K.B.,Selwood, T.,Marquardt, U.,Huber, R.,Schechter, N.M.,Bode, W.,Than, M.E.
X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357:195-209, 2005
Cited by
PubMed: 16414069
DOI: 10.1016/j.jmb.2005.12.037
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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