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5TKK
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BU of 5tkk by Molmil
Structure of mouse vaccination-elicited HIV neutralizing antibody vFP5.01 in complex with HIV-1 fusion peptide residue 512-519
Descriptor: HIV-1 fusion peptide residue 512-519, mouse antibody vFP5.01 heavy chain, mouse antibody vFP5.01 light chain
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2016-10-06
Release date:2018-04-04
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6UPL
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BU of 6upl by Molmil
Structure of FACT_subnucleosome complex 2
Descriptor: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ...
Authors:Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K.
Deposit date:2019-10-17
Release date:2019-12-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:FACT caught in the act of manipulating the nucleosome.
Nature, 577, 2020
6UPK
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BU of 6upk by Molmil
Structure of FACT_subnucleosome complex 1
Descriptor: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ...
Authors:Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K.
Deposit date:2019-10-17
Release date:2019-12-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:FACT caught in the act of manipulating the nucleosome.
Nature, 577, 2020
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-08-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
7RZI
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BU of 7rzi by Molmil
Insulin Degrading Enzyme pC/pC
Descriptor: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
Authors:Mancl, J.M, Liang, W.G, Tang, W.J.
Deposit date:2021-08-27
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZE
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BU of 7rze by Molmil
Insulin Degrading Enzyme pO/pC
Descriptor: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
Authors:Mancl, J.M, Liang, W.G, Tang, W.J.
Deposit date:2021-08-27
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZH
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BU of 7rzh by Molmil
Insulin Degrading Enzyme O/O
Descriptor: Cysteine-free Insulin-degrading enzyme
Authors:Mancl, J.M, Liang, W.G, Tang, W.J.
Deposit date:2021-08-27
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZG
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BU of 7rzg by Molmil
Insulin Degrading Enzyme O/pO
Descriptor: Cysteine-free Insulin-degrading enzyme
Authors:Mancl, J.M, Liang, W.G, Tang, W.J.
Deposit date:2021-08-27
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZF
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BU of 7rzf by Molmil
Insulin Degrading Enzyme O/pC
Descriptor: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
Authors:Mancl, J.M, Liang, W.G, Tang, W.J.
Deposit date:2021-08-27
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
6VFT
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BU of 6vft by Molmil
Crystal structure of human delta protocadherin 17 EC1-EC4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VG4
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BU of 6vg4 by Molmil
Human protocadherin 10 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-07
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFR
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BU of 6vfr by Molmil
Crystal structure of human protocadherin 18 EC1-EC4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFP
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BU of 6vfp by Molmil
Crystal structure of human protocadherin 1 EC1-EC4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin-1, ...
Authors:Brasch, J, Harrison, O.J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFU
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BU of 6vfu by Molmil
Crystal structure of human protocadherin 19 EC1-EC4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VG1
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BU of 6vg1 by Molmil
xenopus protocadherin 8.1 EC1-6
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Harrison, O.J, Brasch, B, Shapiro, L.S.
Deposit date:2020-01-07
Release date:2020-03-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFW
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BU of 6vfw by Molmil
Crystal structure of human delta protocadherin 10 EC1-EC4
Descriptor: CALCIUM ION, Protocadherin-10, alpha-D-mannopyranose, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFQ
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BU of 6vfq by Molmil
Crystal structure of monomeric human protocadherin 10 EC1-EC4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFV
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BU of 6vfv by Molmil
Crystal structure of human protocadherin 8 EC5-EC6
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2020-01-06
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6XOS
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BU of 6xos by Molmil
CryoEM structure of human presequence protease in partial open state 1
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOU
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BU of 6xou by Molmil
CryoEM structure of human presequence protease in open state
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
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BU of 6xov by Molmil
CryoEM structure of human presequence protease in partial closed state 1
Descriptor: Amyloid-beta precursor protein, Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOT
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BU of 6xot by Molmil
CryoEM structure of human presequence protease in partial open state 2
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
6B70
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BU of 6b70 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin
Descriptor: FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ...
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-03
Release date:2017-12-27
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018

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