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4EMP
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BU of 4emp by Molmil
Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Ye, F, Zhang, J, Liu, H, Luo, C, Yang, C.-G.
Deposit date:2012-04-12
Release date:2013-04-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Helix unfolding/refolding characterizes the functional dynamics of Staphylococcus aureus Clp protease
J.Biol.Chem., 288, 2013
4XFV
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BU of 4xfv by Molmil
Crystal Structure of Elp2
Descriptor: Elongator complex protein 2
Authors:Lin, Z, Dong, C, Long, J, Shen, Y.
Deposit date:2014-12-29
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The elp2 subunit is essential for elongator complex assembly and functional regulation
Structure, 23, 2015
7Y3N
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BU of 7y3n by Molmil
Crystal structure of SARS-CoV receptor binding domain in complex with human antibody BIOLS56
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, ...
Authors:Rao, X, Chai, Y, Wu, Y, Gao, F.
Deposit date:2022-06-11
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
7Y3O
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BU of 7y3o by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody BIOLS56
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, Light chain of BIOLS56, ...
Authors:Rao, X, Gao, F, Wu, Y, Gao, F.
Deposit date:2022-06-11
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
7V1N
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BU of 7v1n by Molmil
Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI
Descriptor: Isoform Beta of Tissue factor pathway inhibitor, Toxin B
Authors:Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L.
Deposit date:2021-08-05
Release date:2022-02-23
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
6L4S
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BU of 6l4s by Molmil
cryo-em structure of alpha-synuclein fiber mutation type E46K
Descriptor: Alpha-synuclein
Authors:Li, Y.W, Zhao, K, Liu, C, Li, X.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Parkinson's disease associated mutation E46K of alpha-synuclein triggers the formation of a distinct fibril structure.
Nat Commun, 11, 2020
5WS2
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BU of 5ws2 by Molmil
Crystal structure of mpy-RNase J (mutant S247A), an archaeal RNase J from Methanolobus psychrophilus R15, complex with RNA
Descriptor: RNA (5'-R(P*AP*AP*AP*AP*A)-3'), Ribonuclease J, SULFATE ION, ...
Authors:Li, D.F, Feng, N.
Deposit date:2016-12-05
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:New molecular insights into an archaeal RNase J reveal a conserved processive exoribonucleolysis mechanism of the RNase J family
Mol. Microbiol., 106, 2017
8HRD
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BU of 8hrd by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS74 Fab heavy chain, IMCAS74 Fab light chain, ...
Authors:Zhao, R.C, Wu, L.L, Han, P.
Deposit date:2022-12-15
Release date:2023-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
3VK6
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BU of 3vk6 by Molmil
Crystal structure of a phosphotyrosine binding domain
Descriptor: E3 ubiquitin-protein ligase Hakai, ZINC ION
Authors:Sivaraman, J, Mukherjee, M.
Deposit date:2011-11-09
Release date:2012-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
Embo J., 31, 2012
4BR6
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BU of 4br6 by Molmil
Crystal structure of Chaetomium thermophilum MnSOD
Descriptor: GLYCEROL, MANGANESE (III) ION, SODIUM ION, ...
Authors:Haikarainen, T, Frioux, C, Zhnag, L.-Q, Li, D.-C, Papageorgiou, A.C.
Deposit date:2013-06-04
Release date:2013-12-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Biochemical Characterization of a Manganese Superoxide Dismutase from Chaetomium Thermophilum.
Biochim.Biophys.Acta, 1844, 2014
3IKA
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BU of 3ika by Molmil
Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002
Descriptor: Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide
Authors:Yun, C.-H, Eck, M.J.
Deposit date:2009-08-05
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.
Nature, 462, 2009
7WB0
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BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAZ
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BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAY
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BU of 7way by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state
Descriptor: DNA (27-MER), DNA (33-MER), RNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB1
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BU of 7wb1 by Molmil
PlmCasX-sgRNAv2-dsDNA ternary complex at nts loading state
Descriptor: NTS-DNA, RNA (121-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7LYK
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BU of 7lyk by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYQ
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BU of 7lyq by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYL
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BU of 7lyl by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYO
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BU of 7lyo by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYP
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BU of 7lyp by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYN
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BU of 7lyn by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
6X2B
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BU of 6x2b by Molmil
SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X2C
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BU of 6x2c by Molmil
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
5X3X
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BU of 5x3x by Molmil
2.8A resolution structure of a cobalt energy-coupling factor transporter-CbiMQO
Descriptor: Cobalt ABC transporter ATP-binding protein, Cobalt transport protein CbiM, Uncharacterized protein CbiQ
Authors:Bao, Z, Qi, X, Wang, J, Zhang, P.
Deposit date:2017-02-09
Release date:2017-04-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.788 Å)
Cite:Structure and mechanism of a group-I cobalt energy coupling factor transporter
Cell Res., 27, 2017
6XZ8
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BU of 6xz8 by Molmil
Structure of aldosterone synthase (CYP11B2) in complex with N-[(1R)-1-[5-(6-chloro-1,1-dimethyl-3-oxo-isoindolin-2-yl)-3-pyridyl]ethyl]methanesulfonamide
Descriptor: Cytochrome P450 11B2, mitochondrial, HEME C, ...
Authors:Kuglstatter, A, Joseph, C, Benz, J.
Deposit date:2020-02-03
Release date:2020-06-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.
J.Med.Chem., 63, 2020

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