8WVB
| Crystal structure of Lsd18 mutant S195M | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC | 著者 | Liu, N, Xiao, H.L, Chen, X. | 登録日 | 2023-10-23 | 公開日 | 2023-12-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
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8WVF
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2AOJ
| Crystal structure analysis of HIV-1 protease with a substrate analog P6-PR | 分子名称: | ACETIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOC
| Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOG
| Crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog P2-NC | 分子名称: | ACETIC ACID, GLYCEROL, HIV-1 PROTEASE (RETROPEPSIN), ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOD
| Crystal structure analysis of HIV-1 protease with a substrate analog P2-NC | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, HIV-1 PROTEASE, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOE
| crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog CA-P2 | 分子名称: | ACETIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOF
| Crystal structure analysis of HIV-1 Protease mutant V82A with a substrate analog P1-P6 | 分子名称: | ACETIC ACID, CHLORIDE ION, PEPTIDE INHIBITOR, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2AOI
| Crystal structure analysis of HIV-1 protease with a substrate analog P1-P6 | 分子名称: | PEPTIDE INHIBITOR, POL POLYPROTEIN, SULFATE ION | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2005-08-12 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
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2B5L
| Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein | 分子名称: | Nonstructural protein V, ZINC ION, damage-specific DNA binding protein 1 | 著者 | Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. | 登録日 | 2005-09-28 | 公開日 | 2006-02-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
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3NVN
| Molecular mechanism of guidance cue recognition | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Liu, H, Juo, Z, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. | 登録日 | 2010-07-08 | 公開日 | 2010-09-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1. Cell(Cambridge,Mass.), 142, 2010
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3NVX
| Molecular mechanism of guidance cue recognition | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein A39 | 著者 | Liu, H, Juo, Z, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. | 登録日 | 2010-07-08 | 公開日 | 2010-09-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1. Cell(Cambridge,Mass.), 142, 2010
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3V6G
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3V78
| Crystal Structure of Transcriptional Regulator | 分子名称: | ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | 著者 | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | 登録日 | 2011-12-20 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
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7SGL
| DNA-PK complex of DNA end processing | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | 著者 | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | 登録日 | 2021-10-06 | 公開日 | 2022-01-12 | 最終更新日 | 2022-01-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
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7SH1
| Class II UvrA protein - Ecm16 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Excinuclease ABC subunit UvrA, ... | 著者 | Grade, P, Erlandson, A, Ullah, A, Mathews, I.I, Chen, X, Kim, C.-Y, Mera, P.E. | 登録日 | 2021-10-07 | 公開日 | 2022-10-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi. Sci Rep, 13, 2023
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5GXJ
| Zika Virus NS2B-NS3 protease | 分子名称: | FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | 著者 | Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K. | 登録日 | 2016-09-18 | 公開日 | 2017-05-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Viral protease activation mechanism To Be Published
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5H6X
| The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila | 分子名称: | GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION | 著者 | Zhang, N, Chen, X, Gong, X, Ge, H. | 登録日 | 2016-11-15 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
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3DWQ
| Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | 分子名称: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWA
| Crystal structure of the B-subunit of the AB5 toxin from E. coli | 分子名称: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWP
| Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | 分子名称: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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8W78
| Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase in complex with FAD and 2-oxoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, DODECYL-BETA-D-MALTOSIDE, FI05204p, ... | 著者 | Yang, J, Chen, X, Jin, S, Ding, J. | 登録日 | 2023-08-30 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria. J.Biol.Chem., 300, 2023
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8W7F
| Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase bound with FAD and a sulfate ion | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Yang, J, Chen, X, Jin, S, Ding, J. | 登録日 | 2023-08-30 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria. J.Biol.Chem., 300, 2023
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8W75
| Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Yang, J, Chen, X, Jin, S, Ding, J. | 登録日 | 2023-08-30 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria. J.Biol.Chem., 300, 2023
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3HFH
| Crystal structure of tandem FF domains | 分子名称: | Transcription elongation regulator 1 | 著者 | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | 登録日 | 2009-05-11 | 公開日 | 2009-08-18 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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