7WMD
 
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4XOH
 | | Mechanistic insights into anchorage of the contractile ring from yeast to humans | | 分子名称: | Division mal foutue 1 protein | | 著者 | Chen, Z, Wu, J.-Q, Wang, J, Guan, R, Sun, L, Lee, I.-J, Liu, Y, Chen, M. | | 登録日 | 2015-01-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
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4XOI
 | | Structure of hsAnillin bound with RhoA(Q63L) at 2.1 Angstroms resolution | | 分子名称: | Actin-binding protein anillin, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sun, L, Guan, R, Lee, I.-J, Liu, Y, Chen, M, Wang, J, Wu, J, Chen, Z. | | 登録日 | 2015-01-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | | 主引用文献 | Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
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4MSU
 | | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | | 分子名称: | 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | | 著者 | Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. | | 登録日 | 2013-09-18 | | 公開日 | 2014-03-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept.
J.Med.Chem., 57, 2014
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7TNS
 | | Subpellicular microtubule from detergent-extract Toxoplasma gondii cells | | 分子名称: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TNT
 | | The tubulin-based conoid from detergent-extract Toxoplasma gondii cells | | 分子名称: | Tubulin alpha chain, Tubulin beta chain | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TNQ
 | | The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells | | 分子名称: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | | 著者 | Sun, S.Y, Pintilie, G.D, Chen, M. | | 登録日 | 2022-01-21 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6PT0
 | | Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2 | | 分子名称: | CHOLESTEROL, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, T.H, Xing, C, Zhuang, Y, Feng, Z, Zhou, X.E, Chen, M, Wang, L, Meng, X, Xue, Y, Wang, J, Liu, H, McGuire, T, Zhao, G, Melcher, K, Zhang, C, Xu, H.E, Xie, X.Q. | | 登録日 | 2019-07-14 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Cell, 180, 2020
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2X7J
 | | Structure of the menaquinone biosynthesis protein MenD from Bacillus subtilis | | 分子名称: | 1,2-ETHANEDIOL, 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE, MANGANESE (II) ION, ... | | 著者 | Dawson, A, Chen, M, Fyfe, P.K, Guo, Z, Hunter, W.N. | | 登録日 | 2010-03-01 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure and Reactivity of Bacillus Subtilis Mend Catalyzing the First Committed Step in Menaquinone Biosynthesis.
J.Mol.Biol., 401, 2010
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8EAR
 | | Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | | 著者 | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | | 登録日 | 2022-08-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
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8EAQ
 | | Structure of the full-length IP3R1 channel determined at high Ca2+ | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ... | | 著者 | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | | 登録日 | 2022-08-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
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8FCG
 | | Cryo-EM structure of Chikungunya virus asymmetric unit | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Capsid protein, E1 glycoprotein, ... | | 著者 | Su, G.C, Chmielewsk, D, Kaelber, J, Pintilie, G, Chen, M, Jin, J, Auguste, A, Chiu, W. | | 登録日 | 2022-12-01 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryogenic electron microscopy and tomography reveal imperfect icosahedral symmetry in alphaviruses.
Pnas Nexus, 3, 2024
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8FR7
 | | A hinge glycan regulates spike bending and impacts coronavirus infectivity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pintilie, G, Wilson, E, Chmielewski, D, Schmid, M.F, Jin, J, Chen, M, Singharoy, A, Chiu, W. | | 登録日 | 2023-01-06 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | A hinge glycan regulates spike bending and impacts coronavirus infectivity
To Be Published
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4JHA
 | | Crystal Structure of RSV-Neutralizing Human Antibody D25 | | 分子名称: | D25 antigen-binding fragment heavy chain, D25 light chain | | 著者 | Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S. | | 登録日 | 2013-03-04 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
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4JHW
 | | Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25 | | 分子名称: | D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0 | | 著者 | Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S. | | 登録日 | 2013-03-05 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
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7Y71
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab E7 heavy chain, ... | | 著者 | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | 登録日 | 2022-06-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
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7Y72
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface) | | 分子名称: | Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein | | 著者 | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | 登録日 | 2022-06-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
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5Z3C
 | | Glycosidase E178A | | 分子名称: | GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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5Z3D
 | | Glycosidase F290Y | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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5Z3B
 | | Glycosidase Y48F | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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5Z3A
 | | Glycosidase Wild Type | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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5Z3E
 | | Glycosidase E335A | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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5Z3F
 | | Glycosidase E335A in complex with glucose | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein, ... | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
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3IXT
 | | Crystal Structure of Motavizumab Fab Bound to Peptide Epitope | | 分子名称: | 1,2-ETHANEDIOL, Fusion glycoprotein F1, Motavizumab Fab heavy chain, ... | | 著者 | McLellan, J.S, Chen, M, Kim, A, Yang, Y, Graham, B.S, Kwong, P.D. | | 登録日 | 2009-09-04 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of respiratory syncytial virus neutralization by motavizumab.
Nat.Struct.Mol.Biol., 17, 2010
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3JBB
 | | Characterization of red-shifted phycobiliprotein complexes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris | | 分子名称: | PHYCOCYANOBILIN, SULFATE ION, allophycocyanin beta chain, ... | | 著者 | Li, Y, Lin, Y, Garvey, C, Birch, D, Corkery, R.W, Loughlin, P.C, Scheer, H, Willows, R.D, Chen, M. | | 登録日 | 2015-08-26 | | 公開日 | 2015-11-11 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (26 Å) | | 主引用文献 | Characterization of red-shifted phycobilisomes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris.
Biochim.Biophys.Acta, 1857, 2015
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