3IXT

Crystal Structure of Motavizumab Fab Bound to Peptide Epitope

Summary for 3IXT

Entry DOI	10.2210/pdb3ixt/pdb
Descriptor	Motavizumab Fab light chain, Motavizumab Fab heavy chain, Fusion glycoprotein F1, ... (5 entities in total)
Functional Keywords	fab, rsv, synagis, motavizumab, monoclonal, complex, cell membrane, cleavage on pair of basic residues, disulfide bond, envelope protein, fusion protein, glycoprotein, lipoprotein, membrane, palmitate, transmembrane, virion, immune system
Biological source	Mus musculus (mouse) More
Cellular location	Virion membrane; Single-pass type I membrane protein: P03420
Total number of polymer chains	6
Total formula weight	100574.88
Authors	McLellan, J.S.,Chen, M.,Kim, A.,Yang, Y.,Graham, B.S.,Kwong, P.D. (deposition date: 2009-09-04, release date: 2010-01-19, Last modification date: 2023-09-06)
Primary citation	McLellan, J.S.,Chen, M.,Kim, A.,Yang, Y.,Graham, B.S.,Kwong, P.D. Structural basis of respiratory syncytial virus neutralization by motavizumab. Nat.Struct.Mol.Biol., 17:248-250, 2010 Cited by PubMed: 20098425 DOI: 10.1038/nsmb.1723 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation