1JNL
| Crystal Structure of Fab-Estradiol Complexes | Descriptor: | monoclonal anti-estradiol 17E12E5 immunoglobulin gamma-1 chain, monoclonal anti-estradiol 17E12E5 immunoglobulin kappa chain | Authors: | Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B. | Deposit date: | 2001-07-24 | Release date: | 2002-02-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Highly specific anti-estradiol antibodies: structural characterisation and binding diversity. J.Mol.Biol., 315, 2002
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1JN6
| Crystal Structure of Fab-Estradiol Complexes | Descriptor: | monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain | Authors: | Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B. | Deposit date: | 2001-07-23 | Release date: | 2002-02-06 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Highly specific anti-estradiol antibodies: structural characterisation and binding diversity. J.Mol.Biol., 315, 2002
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1BQ7
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1YED
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1YEE
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1YEC
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1KNO
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7ZT6
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7ZVT
| CryoEM structure of Ku heterodimer bound to DNA | Descriptor: | DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*T)-3'), DNA (5'-D(P*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*TP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | Deposit date: | 2022-05-17 | Release date: | 2023-05-24 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction. Nucleic Acids Res., 51, 2023
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7ZWA
| CryoEM structure of Ku heterodimer bound to DNA and PAXX | Descriptor: | DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ... | Authors: | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | Deposit date: | 2022-05-19 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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7ZYG
| CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF | Descriptor: | DNA, Non-homologous end-joining factor 1, PHOSPHATE ION, ... | Authors: | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | Deposit date: | 2022-05-24 | Release date: | 2023-06-07 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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2YGV
| Conserved N-terminal domain of the yeast Histone Chaperone Asf1 in complex with the C-terminal fragment of Rad53 | Descriptor: | GLYCEROL, HISTONE CHAPERONE ASF1, SERINE/THREONINE-PROTEIN KINASE RAD53, ... | Authors: | Jiao, Y, Seeger, K, Murciano, B, Ledu, M.H, Charbonnier, J.B, Legrand, P, Lautrette, A, Gaubert, A, Mousson, F, Guerois, R, Mann, C, Ochsenbein, F. | Deposit date: | 2011-04-21 | Release date: | 2012-02-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Surprising Complexity of the Asf1 Histone Chaperone-Rad53 Kinase Interaction Proc.Natl.Acad.Sci.USA, 109, 2012
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8BOT
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8BH3
| DNA-PK Ku80 mediated dimer bound to PAXX | Descriptor: | DNA (25-MER), DNA (26-MER), DNA (27-MER), ... | Authors: | Hardwick, S.W, Chaplin, A.K. | Deposit date: | 2022-10-28 | Release date: | 2023-06-07 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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8BHV
| DNA-PK XLF mediated dimer bound to PAXX | Descriptor: | DNA (24-MER), DNA (26-MER), DNA (27-MER), ... | Authors: | Hardwick, S.W, Chaplin, A.K. | Deposit date: | 2022-11-01 | Release date: | 2023-06-07 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.51 Å) | Cite: | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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8BHY
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1YEJ
| CATALYTIC ANTIBODY COMPLEX | Descriptor: | 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1998-08-13 | Release date: | 1999-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. J.Mol.Biol., 284, 1998
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1YEG
| STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT | Descriptor: | ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1997-05-29 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
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1YEI
| CATALYTIC ANTIBODY D2.3 COMPLEX | Descriptor: | PARA-NITROPHENYLPHOSPHONOBUTANOYL-GLYCINE, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1998-08-13 | Release date: | 1999-01-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. J.Mol.Biol., 284, 1998
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1YEK
| CATALYTIC ANTIBODY D2.3 COMPLEX | Descriptor: | P-NITROPHENOL, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1998-08-13 | Release date: | 1999-01-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. J.Mol.Biol., 284, 1998
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1YEF
| STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE | Descriptor: | IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1997-05-29 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
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1YEH
| STRUCTURE OF IGG2A FAB FRAGMENT | Descriptor: | FAB FRAGMENT, ZINC ION | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1997-05-29 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
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3G5F
| Crystallographic analysis of cytochrome P450 cyp121 | Descriptor: | Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Belin, P, Le Du, M.H, Gondry, M. | Deposit date: | 2009-02-05 | Release date: | 2009-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5H
| Crystallographic analysis of cytochrome P450 cyp121 | Descriptor: | (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Belin, P, Le Du, M.H, Gondry, M. | Deposit date: | 2009-02-05 | Release date: | 2009-04-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
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7NFC
| Cryo-EM structure of NHEJ super-complex (dimer) | Descriptor: | DNA (27-MER), DNA (28-MER), DNA ligase 4, ... | Authors: | Chaplin, A.K, Hardwick, S.W, Kefala Stavridi, A, Chirgadze, D.Y, Blundell, T.L. | Deposit date: | 2021-02-05 | Release date: | 2021-08-18 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Cryo-EM of NHEJ supercomplexes provides insights into DNA repair. Mol.Cell, 81, 2021
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