3G5H
Crystallographic analysis of cytochrome P450 cyp121
Summary for 3G5H
Entry DOI | 10.2210/pdb3g5h/pdb |
Related | 1N40 3G5F |
Descriptor | Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, ... (5 entities in total) |
Functional Keywords | cytochrome p450, cyp121, tuberculosis, cyclodipeptide, substrate, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 44344.76 |
Authors | Belin, P.,Le Du, M.H.,Gondry, M. (deposition date: 2009-02-05, release date: 2009-04-21, Last modification date: 2024-03-20) |
Primary citation | Belin, P.,Le Du, M.H.,Fielding, A.,Lequin, O.,Jacquet, M.,Charbonnier, J.B.,Lecoq, A.,Thai, R.,Courcon, M.,Masson, C.,Dugave, C.,Genet, R.,Pernodet, J.L.,Gondry, M. Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106:7426-7431, 2009 Cited by PubMed: 19416919DOI: 10.1073/pnas.0812191106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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