8BH3

DNA-PK Ku80 mediated dimer bound to PAXX

Summary for 8BH3

Entry DOI	10.2210/pdb8bh3/pdb
EMDB information	16044
Descriptor	DNA-dependent protein kinase catalytic subunit, DNA (28-MER), X-ray repair cross-complementing protein 6, ... (10 entities in total)
Functional Keywords	dna-pk, dna-pkcs, ku70, ku80, paxx, nhej, dna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	18
Total formula weight	1682468.39
Authors	Hardwick, S.W.,Chaplin, A.K. (deposition date: 2022-10-28, release date: 2023-06-07, Last modification date: 2023-06-14)
Primary citation	Seif-El-Dahan, M.,Kefala-Stavridi, A.,Frit, P.,Hardwick, S.W.,Chirgadze, D.Y.,Maia De Oliviera, T.,Britton, S.,Barboule, N.,Bossaert, M.,Pandurangan, A.P.,Meek, K.,Blundell, T.L.,Ropars, V.,Calsou, P.,Charbonnier, J.B.,Chaplin, A.K. PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9:eadg2834-eadg2834, 2023 Cited by PubMed: 37256950 DOI: 10.1126/sciadv.adg2834 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.55 Å)

Structure validation