3Q48
| Crystal structure of Pseudomonas aeruginosa CupB2 chaperone | Descriptor: | Chaperone CupB2 | Authors: | Cai, X, Wang, R, Filloux, A, Waksman, G, Meng, G. | Deposit date: | 2010-12-23 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones Plos One, 6, 2011
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4HRV
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7CU8
| Crystal structure of the soluble domain of TiME protein from Mycobacterium tuberculosis | Descriptor: | SULFATE ION, Tube-forming protein in Mycobacterial Envelope (TiME) | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | Deposit date: | 2020-08-21 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope. Sci Adv, 7, 2021
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7CU9
| Crystal structure of the soluble domain of TiME protein from Mycobacterium smegmatis | Descriptor: | GLYCEROL, MAGNESIUM ION, Tube-forming protein in Mycobacterial Envelpe, ... | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | Deposit date: | 2020-08-21 | Release date: | 2021-08-25 | Last modified: | 2022-03-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope. Sci Adv, 7, 2021
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1EEU
| M4L/Y(27D)D/Q89D/T94H mutant of LEN | Descriptor: | ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-02-03 | Release date: | 2001-02-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11, 2002
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1EFQ
| Q38D mutant of LEN | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-02-09 | Release date: | 2001-02-09 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11, 2002
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1QAC
| CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE | Descriptor: | IMMUNOGLOBULIN LIGHT CHAIN VARIABLE DOMAIN | Authors: | Pokkuluri, P.R, Cai, X, Johnson, G, Stevens, F.J, Schiffer, M. | Deposit date: | 1999-02-25 | Release date: | 2000-02-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface. Protein Sci., 9, 2000
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7D72
| Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, Mannose-1-phosphate guanyltransferase alpha, ... | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | Deposit date: | 2020-10-02 | Release date: | 2021-05-05 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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7D73
| Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, ... | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | Deposit date: | 2020-10-02 | Release date: | 2021-05-05 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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7D74
| Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, Mannose-1-phosphate guanyltransferase beta | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, cai, X, Mo, X, Gao, N, Jia, D. | Deposit date: | 2020-10-02 | Release date: | 2021-05-19 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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7CZ5
| Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | Descriptor: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-07 | Release date: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for activation of the growth hormone-releasing hormone receptor. Nat Commun, 11, 2020
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3TEQ
| Crystal structure of SOAR domain | Descriptor: | PHOSPHATE ION, Stromal interaction molecule 1 | Authors: | Yang, X, Jin, H, Cai, X, Shen, Y. | Deposit date: | 2011-08-15 | Release date: | 2012-04-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1). Proc.Natl.Acad.Sci.USA, 109, 2012
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3TER
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6EWS
| Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12A-NDD | Descriptor: | NRPS Kj12A-NDD | Authors: | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | Deposit date: | 2017-11-06 | Release date: | 2018-10-31 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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6EWV
| Solution Structure of Docking Domain Complex of RXP NRPS: Kj12C NDD - Kj12B CDD | Descriptor: | NRPS Kj12C-NDD, NRPS Kj12B-CDD | Authors: | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | Deposit date: | 2017-11-06 | Release date: | 2018-10-31 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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6EWT
| Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12B-NDD | Descriptor: | NRPS Kj12B-NDD | Authors: | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | Deposit date: | 2017-11-06 | Release date: | 2018-10-31 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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6EWU
| Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12C-NDD | Descriptor: | NRPS Kj12C-NDD | Authors: | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | Deposit date: | 2017-11-06 | Release date: | 2018-10-31 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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7D68
| Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex | Descriptor: | Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-29 | Release date: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor. Cell Res., 30, 2020
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5V54
| Crystal structure of 5-HT1B receptor in complex with methiothepin | Descriptor: | 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine, 5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B | Authors: | Yin, W.C, Zhou, X.E, Yang, D, de Waal, P, Wang, M.T, Dai, A, Cai, X, Huang, C.Y, Liu, P, Yin, Y, Liu, B, Caffrey, M, Melcher, K, Xu, Y, Wang, M.W, Xu, H.E, Jiang, Y. | Deposit date: | 2017-03-13 | Release date: | 2018-02-07 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist Cell Discov, 2018
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5VEW
| Structure of the human GLP-1 receptor complex with PF-06372222 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, ... | Authors: | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | Deposit date: | 2017-04-05 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
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5VEX
| Structure of the human GLP-1 receptor complex with NNC0640 | Descriptor: | 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, Glucagon-like peptide 1 receptor, Endolysin chimera | Authors: | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | Deposit date: | 2017-04-05 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
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2J0M
| Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase. Cell(Cambridge,Mass.), 129, 2007
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2J0K
| Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase. Cell(Cambridge,Mass.), 129, 2007
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2J0J
| Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell(Cambridge,Mass.), 129, 2007
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2J0L
| Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop. | Descriptor: | FOCAL ADHESION KINASE 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell(Cambridge,Mass.), 129, 2007
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