6MXD
 
 | |
6NC5
 | | Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif | | Descriptor: | ACETATE ION, Beta-lactamase, PHOSPHATE ION, ... | | Authors: | Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G. | | Deposit date: | 2018-12-10 | | Release date: | 2019-12-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.074 Å) | | Cite: | Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse.
Protein Cell, 11, 2020
|
|
8YMK
 | | Localized reconstruction of Hepatitis B virus surface antigen dimer in the subviral particle with D2 symmetry from dataset A0 | | Descriptor: | Isoform S of Large envelope protein | | Authors: | Wang, T, Cao, L, Mu, A, Wang, Q, Rao, Z.H. | | Deposit date: | 2024-03-09 | | Release date: | 2024-09-18 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Inherent symmetry and flexibility in hepatitis B virus subviral particles.
Science, 385, 2024
|
|
8YMJ
 | | Cryo-EM structure of Hepatitis B virus surface antigen subviral particle with D2 symmetry | | Descriptor: | Isoform S of Large envelope protein | | Authors: | Wang, T, Cao, L, Mu, A, Wang, Q, Rao, Z.H. | | Deposit date: | 2024-03-09 | | Release date: | 2024-09-18 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Inherent symmetry and flexibility in hepatitis B virus subviral particles.
Science, 385, 2024
|
|
5VEJ
 | |
6G46
 | |
5YJZ
 | | The native crystal structure of Rv3197 from Mycobacterium tuberculosis | | Descriptor: | GLYCEROL, Probable conserved ATP-binding protein ABC transporter, SULFATE ION | | Authors: | Zhang, Q.Q, Rao, Z.H. | | Deposit date: | 2017-10-11 | | Release date: | 2018-02-07 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
Protein Cell, 9, 2018
|
|
5YK1
 | | The complex structure of Rv3197-AMPPNP from Mycobacterium tuberculosis | | Descriptor: | GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable conserved ATP-binding protein ABC transporter, ... | | Authors: | Rao, Z.H, Zhang, Q.Q. | | Deposit date: | 2017-10-11 | | Release date: | 2018-02-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.103 Å) | | Cite: | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
Protein Cell, 9, 2018
|
|
5YK0
 | | The complex structure of Rv3197-ADP from Mycobacterium tuberculosis | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Probable conserved ATP-binding protein ABC transporter, ... | | Authors: | Rao, Z.H, Zhang, Q.Q. | | Deposit date: | 2017-10-11 | | Release date: | 2018-02-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
Protein Cell, 9, 2018
|
|
5YK2
 | |
8UAJ
 | | Succinate Bound Crystal Structure of Thermus scotoductus SA-01 Ene-reductase | | Descriptor: | FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase, SUCCINIC ACID | | Authors: | Wilson, L.A, Guddat, L, Schenk, G, Scott, C. | | Deposit date: | 2023-09-21 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structural Characterization of Enzymatic Interactions with Functional Nicotinamide Cofactor Biomimetics
Catalysts, 14, 2024
|
|
7VAH
 | |
5JV5
 | |
5KAP
 | |
5KAM
 | |
5JSQ
 | |
5K51
 | |
6LU7
 | | The crystal structure of COVID-19 main protease in complex with an inhibitor N3 | | Descriptor: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | Authors: | Liu, X, Zhang, B, Jin, Z, Yang, H, Rao, Z. | | Deposit date: | 2020-01-26 | | Release date: | 2020-02-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Structure of Mprofrom SARS-CoV-2 and discovery of its inhibitors.
Nature, 582, 2020
|
|
6MFI
 | | MIM-2 Metallo-Beta-Lactamase | | Descriptor: | Metallo-beta-lactamase, ZINC ION | | Authors: | Selleck, C, Guddat, L, Schenk, G, Monteiro Pedroso, M. | | Deposit date: | 2018-09-11 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.839 Å) | | Cite: | characterization of the B3 MBLs MIM-1 and MIM-2 from environmental microorganisms.
Chemistry, 23, 2017
|
|
6MXC
 | |
6APT
 | | Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | | Descriptor: | DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | | Authors: | Teran, D, Guddat, L.W. | | Deposit date: | 2017-08-17 | | Release date: | 2018-03-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.795 Å) | | Cite: | Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
|
|
6APS
 | | Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with [(2-((Guanine-9H-yl)methyl)propane-1,3 diyl)bis(oxy)]bis(methylene))diphosphonic acid | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, ... | | Authors: | Teran, D, Guddat, L.W. | | Deposit date: | 2017-08-17 | | Release date: | 2018-03-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.762 Å) | | Cite: | Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
|
|
6APV
 | |
7WNX
 | | Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs | | Descriptor: | N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3 | | Authors: | Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z. | | Deposit date: | 2022-01-20 | | Release date: | 2022-08-03 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.
Structure, 30, 2022
|
|
7WIW
 | | Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | | Authors: | Zhang, B, Sun, S, Yang, H, Rao, Z. | | Deposit date: | 2022-01-05 | | Release date: | 2023-01-25 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
|
|
