5K51
Trypanosome brucei Hypoxanthine-guanine phosphoribosyltranferase in complex with a 9-[5-(phosphonoheptyl]hypoxanthine
Summary for 5K51
| Entry DOI | 10.2210/pdb5k51/pdb |
| Related | 5JSQ 5JV5 5KAM 5KAP |
| Descriptor | Hypoxanthine-guanine phosphoribosyltransferase, 5-(6-oxidanylidene-3~{H}-purin-9-yl)pentylphosphonic acid (3 entities in total) |
| Functional Keywords | inhibitor, complex, dimer, enzyme, transferase |
| Biological source | Trypanosoma brucei brucei |
| Cellular location | Cytoplasm: Q07010 |
| Total number of polymer chains | 4 |
| Total formula weight | 98032.00 |
| Authors | Teran, D.,Guddat, L. (deposition date: 2016-05-22, release date: 2016-11-09, Last modification date: 2023-09-27) |
| Primary citation | Teran, D.,Hockova, D.,Cesnek, M.,Zikova, A.,Naesens, L.,Keough, D.T.,Guddat, L.W. Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase. Sci Rep, 6:35894-35894, 2016 Cited by PubMed: 27786284DOI: 10.1038/srep35894 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.956 Å) |
Structure validation
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