5WKC

Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam

Summary for 5WKC

Entry DOI	10.2210/pdb5wkc/pdb
Descriptor	Acetolactate synthase catalytic subunit, mitochondrial, MAGNESIUM ION, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, ... (9 entities in total)
Functional Keywords	ahas, acetohydroxyacid synthase; scahas; thiamine diphosphate; flavin adenine dinucleotide; penoxsulam; aminoethenethiol diphosphate; peracetate., structural protein, transferase
Biological source	Saccharomyces cerevisiae S288c (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	301545.94
Authors	Guddat, W.L.,Lonhienne, G.T. (deposition date: 2017-07-25, release date: 2018-02-14, Last modification date: 2023-10-04)
Primary citation	Lonhienne, T.,Garcia, M.D.,Pierens, G.,Mobli, M.,Nouwens, A.,Guddat, L.W. Structural insights into the mechanism of inhibition of AHAS by herbicides. Proc. Natl. Acad. Sci. U.S.A., 115:E1945-E1954, 2018 Cited by PubMed: 29440497 DOI: 10.1073/pnas.1714392115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.334 Å)

Structure validation