6MXB

Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in complex with XMP

Summary for 6MXB

Entry DOI	10.2210/pdb6mxb/pdb
Descriptor	Hypoxanthine-guanine phosphoribosyltransferase, putative, XANTHOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	6-oxopurine prts, purine salvage, transferase
Biological source	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Total number of polymer chains	6
Total formula weight	186098.18
Authors	Teran, D.,Guddat, L. (deposition date: 2018-10-30, release date: 2019-07-24, Last modification date: 2023-10-11)
Primary citation	Teran, D.,Dolezelova, E.,Keough, D.T.,Hockova, D.,Zikova, A.,Guddat, L.W. Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP. Febs J., 286:4721-4736, 2019 Cited by PubMed: 31287615 DOI: 10.1111/febs.14987 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.192 Å)

Structure validation