5KAM

Trypanosome brucei Hypoxanthine-guanine phosphoribosyltranferase in complex with Inosine 5' monophosphate

Summary for 5KAM

Entry DOI	10.2210/pdb5kam/pdb
Related	5JSQ 5JV5 5K51 5KAP
Descriptor	Hypoxanthine-guanine phosphoribosyltransferase, INOSINIC ACID, SULFATE ION, ... (5 entities in total)
Functional Keywords	inhibitor, complex, dimer, enzyme, transferase
Biological source	Trypanosoma brucei brucei
Cellular location	Cytoplasm: Q07010
Total number of polymer chains	2
Total formula weight	49645.74
Authors	Teran, D.,Guddat, L. (deposition date: 2016-06-01, release date: 2016-11-09, Last modification date: 2023-09-27)
Primary citation	Teran, D.,Hockova, D.,Cesnek, M.,Zikova, A.,Naesens, L.,Keough, D.T.,Guddat, L.W. Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase. Sci Rep, 6:35894-35894, 2016 Cited by PubMed: 27786284 DOI: 10.1038/srep35894 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.481 Å)

Structure validation