6G46

Red kidney bean purple acid phosphatase in complex with 2-(Naphthalen-1-yl)thiazole-4-carboxylic acid

Summary for 6G46

Entry DOI	10.2210/pdb6g46/pdb
Descriptor	Fe(3+)-Zn(2+) purple acid phosphatase, SODIUM ION, ISOPROPYL ALCOHOL, ... (13 entities in total)
Functional Keywords	phosphatase, metallohydrolase, hydrolase, metalloprotein, purple acid phosphatase, pap, red kidney bean, rkbpap, drug design, drug discovery, rational drug design, osteoporosis, metal binding protein
Biological source	Phaseolus vulgaris (Kidney bean)
Total number of polymer chains	4
Total formula weight	206715.09
Authors	Feder, D.F. (deposition date: 2018-03-26, release date: 2018-09-26, Last modification date: 2024-01-17)
Primary citation	Hussein, W.M.,Feder, D.,Schenk, G.,Guddat, L.W.,McGeary, R.P. Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics. Eur J Med Chem, 157:462-479, 2018 Cited by PubMed: 30107365 DOI: 10.1016/j.ejmech.2018.08.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation