7AC1
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![BU of 7ac1 by Molmil](/molmil-images/mine/7ac1) | Solution structure of the TAF4-RST domain | Descriptor: | Transcription initiation factor TFIID subunit 4 | Authors: | Staby, L, Davidsen, R, Bugge, K, Skriver, K, Kragelund, B.B. | Deposit date: | 2020-09-09 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | alpha alpha-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes. J.Biol.Chem., 298, 2022
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5F2E
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![BU of 5f2e by Molmil](/molmil-images/mine/5f2e) | Crystal Structure of small molecule ARS-853 covalently bound to K-Ras G12C | Descriptor: | 1-[3-[4-[2-[[4-chloranyl-5-(1-methylcyclopropyl)-2-oxidanyl-phenyl]amino]ethanoyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one, GLYCEROL, GLYCINE, ... | Authors: | Patricelli, M.P, Janes, M.R, Li, L.-S, Hansen, R, Peters, U, Kessler, L.V, Chen, Y, Kucharski, J.M, Feng, J, Ely, T, Chen, J.H, Firdaus, S.J, Babbar, A, Ren, P, Liu, Y. | Deposit date: | 2015-12-01 | Release date: | 2016-01-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State. Cancer Discov, 6, 2016
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6Z5N
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![BU of 6z5n by Molmil](/molmil-images/mine/6z5n) | DnaJB1 JD-GF | Descriptor: | DnaJ homolog subfamily B member 1 | Authors: | Avraham-Abayev, M, London, N, Rosenzweig, R. | Deposit date: | 2020-05-27 | Release date: | 2020-11-18 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | HSP40 proteins use class-specific regulation to drive HSP70 functional diversity. Nature, 587, 2020
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7ZYI
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![BU of 7zyi by Molmil](/molmil-images/mine/7zyi) | Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody | Descriptor: | CHOLESTEROL, GLYCOCHENODEOXYCHOLIC ACID, Nanobody, ... | Authors: | Liu, H, Irobalieva, R.N, Bang-Sorensen, R, Nosol, K, Mukherjee, S, Agrawal, P, Stieger, B, Kossiakoff, A.A, Locher, K.P. | Deposit date: | 2022-05-24 | Release date: | 2022-07-13 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Res., 32, 2022
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6FXB
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![BU of 6fxb by Molmil](/molmil-images/mine/6fxb) | Bovine beta-lactoglobulin variant A at pH 4.0 | Descriptor: | DI(HYDROXYETHYL)ETHER, Major allergen beta-lactoglobulin, NITRATE ION | Authors: | Khan, S, Ipsen, R, Almdal, K, Svensson, B, Harris, P. | Deposit date: | 2018-03-08 | Release date: | 2018-05-23 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Revealing the Dimeric Crystal and Solution Structure of beta-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer-Dimer Equilibrium. Biomacromolecules, 19, 2018
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4ZD3
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![BU of 4zd3 by Molmil](/molmil-images/mine/4zd3) | Structure of a transglutaminase 2-specific autoantibody Fab fragment | Descriptor: | 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain | Authors: | Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. | Deposit date: | 2015-04-16 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease. J.Biol.Chem., 290, 2015
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3Q9O
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3J8Y
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![BU of 3j8y by Molmil](/molmil-images/mine/3j8y) | High-resolution structure of ATP analog-bound kinesin on microtubules | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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3J8X
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![BU of 3j8x by Molmil](/molmil-images/mine/3j8x) | High-resolution structure of no-nucleotide kinesin on microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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3NY6
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![BU of 3ny6 by Molmil](/molmil-images/mine/3ny6) | Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30 | Descriptor: | 2-[(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide, Cholix toxin, GLYCEROL, ... | Authors: | Merrill, A.R, Jorgensen, R. | Deposit date: | 2010-07-14 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins. Antimicrob.Agents Chemother., 55, 2011
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4CVB
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![BU of 4cvb by Molmil](/molmil-images/mine/4cvb) | Crystal structure of quinone-dependent alcohol dehydrogenase from Pseudogluconobacter saccharoketogenenes | Descriptor: | ALCOHOL DEHYDROGENASE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Rozeboom, H.J, Yu, S, Mikkelsen, R, Nikolaev, I, Mulder, H, Dijkstra, B.W. | Deposit date: | 2014-03-25 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal Structure of Quinone-Dependent Alcohol Dehydrogenase from Pseudogluconobacter Saccharoketogenes. A Versatile Dehydrogenase Oxidizing Alcohols and Carbohydrates. Protein Sci., 24, 2015
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4CVC
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![BU of 4cvc by Molmil](/molmil-images/mine/4cvc) | Crystal structure of quinone-dependent alcohol dehydrogenase from Pseudogluconobacter saccharoketogenenes with zinc in the active site | Descriptor: | ALCOHOL DEHYDROGENASE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Rozeboom, H.J, Yu, S, Mikkelsen, R, Nikolaev, I, Mulder, H, Dijkstra, B.W. | Deposit date: | 2014-03-25 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure of Quinone-Dependent Alcohol Dehydrogenase from Pseudogluconobacter Saccharoketogenes. A Versatile Dehydrogenase Oxidizing Alcohols and Carbohydrates. Protein Sci., 24, 2015
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2W0C
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![BU of 2w0c by Molmil](/molmil-images/mine/2w0c) | X-ray structure of the entire lipid-containing bacteriophage PM2 | Descriptor: | CALCIUM ION, MAJOR CAPSID PROTEIN P2, PROTEIN 2, ... | Authors: | Abrescia, N.G.A, Grimes, J.M, Kivela, H.M, Assenberg, R, Sutton, G.C, Butcher, S.J, Bamford, J.K.H, Bamford, D.H, Stuart, D.I. | Deposit date: | 2008-08-13 | Release date: | 2008-09-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2 Mol.Cell, 31, 2008
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1CWQ
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![BU of 1cwq by Molmil](/molmil-images/mine/1cwq) | M INTERMEDIATE STRUCTURE OF THE WILD TYPE BACTERIORHODOPSIN IN COMBINATION WITH THE GROUND STATE STRUCTURE | Descriptor: | BACTERIORHODOPSIN ("M" STATE INTERMEDIATE IN COMBINATION WITH GROUND STATE), HEXANE, N-OCTANE, ... | Authors: | Sass, H.J, Berendzen, J, Neff, D, Gessenich, R, Ormos, P, Bueldt, G. | Deposit date: | 1999-08-26 | Release date: | 1999-10-20 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin. Nature, 406, 2000
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1XK9
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![BU of 1xk9 by Molmil](/molmil-images/mine/1xk9) | Pseudomanas exotoxin A in complex with the PJ34 inhibitor | Descriptor: | Exotoxin A, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | Authors: | Yates, S.P, Taylor, P.J, Joergensen, R, Ferrraris, D, Zhang, J, Andersen, G.R, Merrill, A.R. | Deposit date: | 2004-09-28 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa BIOCHEM.J., 385, 2005
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3IOH
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![BU of 3ioh by Molmil](/molmil-images/mine/3ioh) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) | Descriptor: | GLYCEROL, Histo-blood group ABO system transferase | Authors: | Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. | Deposit date: | 2009-08-14 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat.Chem.Biol., 6, 2010
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2CBV
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2CBU
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![BU of 2cbu by Molmil](/molmil-images/mine/2cbu) | Beta-glucosidase from Thermotoga maritima in complex with castanospermine | Descriptor: | ACETATE ION, BETA-GLUCOSIDASE A, CALCIUM ION, ... | Authors: | Gloster, T.M, Davies, G.J, Madsen, R. | Deposit date: | 2006-01-09 | Release date: | 2006-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Dissection of Conformationally Restricted Inhibitors Binding to a Beta-Glucosidase. Chembiochem, 7, 2006
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2FJN
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![BU of 2fjn by Molmil](/molmil-images/mine/2fjn) | The structure of phosphotyrosine phosphatase 1B in complex with compound 2 | Descriptor: | (4-{(2S,4E)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-[4-(METHOXYCARBONYL)PHENYL]-5-PHENYLPENT-4-ENYL}PHENYL)(DIFLUORO)METHYLPHOSPHONIC ACID, CHLORIDE ION, Tyrosine-protein phosphatase, ... | Authors: | Asante-Appiah, E, Patel, S, Desponts, C, Taylor, J.M, Lau, C, Dufresne, C, Therien, M, Friesen, R, Becker, J.W, Leblanc, Y, Kennedy, B.P, Scapin, G. | Deposit date: | 2006-01-03 | Release date: | 2006-01-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. J.Biol.Chem., 281, 2006
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2FJM
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![BU of 2fjm by Molmil](/molmil-images/mine/2fjm) | The structure of phosphotyrosine phosphatase 1B in complex with compound 2 | Descriptor: | (4-{(2S,4E)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-[4-(METHOXYCARBONYL)PHENYL]-5-PHENYLPENT-4-ENYL}PHENYL)(DIFLUORO)METHYLPHOSPHONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Asante-Appiah, E, Patel, S, Desponts, C, Taylor, J.M, Lau, C, Dufresne, C, Therien, M, Friesen, R, Becker, J.W, Leblanc, Y, Scapin, G. | Deposit date: | 2006-01-03 | Release date: | 2006-01-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. J.Biol.Chem., 281, 2006
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2CME
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![BU of 2cme by Molmil](/molmil-images/mine/2cme) | The crystal structure of SARS coronavirus ORF-9b protein | Descriptor: | DECANE, HYPOTHETICAL PROTEIN 5 | Authors: | Meier, C, Aricescu, A.R, Assenberg, R, Aplin, R.T, Gilbert, R.J.C, Grimes, J.M, Stuart, D.I. | Deposit date: | 2006-05-06 | Release date: | 2006-07-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of Orf-9B, a Lipid Binding Protein from the Sars Coronavirus. Structure, 14, 2006
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2V8O
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![BU of 2v8o by Molmil](/molmil-images/mine/2v8o) | Structure of the Murray Valley encephalitis virus RNA helicase to 1. 9A resolution | Descriptor: | FLAVIVIRIN PROTEASE NS3 | Authors: | Mancini, E.J, Assenberg, R, Verma, A, Walter, T.S, Tuma, R, Grimes, J.M, Owens, R.J, Stuart, D.I. | Deposit date: | 2007-08-09 | Release date: | 2007-08-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Murray Valley Encephalitis Virus RNA Helicase at 1.9 A Resolution. Protein Sci., 16, 2007
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2CKJ
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![BU of 2ckj by Molmil](/molmil-images/mine/2ckj) | Human milk xanthine oxidoreductase | Descriptor: | ACETIC ACID, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Pearson, A.R, Godber, B.L.J, Eisenthal, R, Taylor, G.L, Harrison, R. | Deposit date: | 2006-04-19 | Release date: | 2007-05-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Human Milk Xanthine Dehydrogenase is Incompletely Converted to the Oxidase Form in the Absence of Proteolysis. A Structural Explanation. To be Published
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2JAL
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![BU of 2jal by Molmil](/molmil-images/mine/2jal) | Beta-glucosidase from Thermotoga maritima in complex with cyclophellitol | Descriptor: | (1R,2S,3S,4S,5R,6R)-6-(HYDROXYMETHYL)CYCLOHEXANE-1,2,3,4,5-PENTOL, ACETATE ION, BETA-GLUCOSIDASE A, ... | Authors: | Gloster, T.M, Madsen, R, Davies, G.J. | Deposit date: | 2006-11-29 | Release date: | 2007-01-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Cyclophellitol Inhibition of a Beta-Glucosidase. Org.Biomol.Chem., 5, 2007
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3IOJ
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![BU of 3ioj by Molmil](/molmil-images/mine/3ioj) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP | Descriptor: | GLYCEROL, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. | Deposit date: | 2009-08-14 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat.Chem.Biol., 6, 2010
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