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3RPI
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BU of 3rpi by Molmil
Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from highly potent anti-HIV neutralizing antibody, Light chain from highly potent anti-HIV neutralizing antibody
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science, 333, 2011
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Descriptor: Ab1303 Fab heavy chain, Ab1303 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
Descriptor: Ab1573 Fab heavy chain, Ab1573 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
2GJ7
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BU of 2gj7 by Molmil
Crystal Structure of a gE-gI/Fc complex
Descriptor: Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
Deposit date:2006-03-30
Release date:2006-05-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (5 Å)
Cite:Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GIY
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BU of 2giy by Molmil
Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain
Descriptor: Glycoprotein E
Authors:Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
Deposit date:2006-03-29
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GSG
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BU of 2gsg by Molmil
Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine
Descriptor: SULFATE ION, monoclonal antibody heavy chain, monoclonal antibody light chain
Authors:Li, P, Huey-Tubman, K.E, West Jr, A.P, Bennett, M.J, Bjorkman, P.J.
Deposit date:2006-04-26
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
2GW5
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BU of 2gw5 by Molmil
Crystal Structure of LIR-2 (ILT4) at 1.8 : differences from LIR-1 (ILT2) in regions implicated in the binding of the Cytomegalovirus class I MHC homolog UL18
Descriptor: ISOPROPYL ALCOHOL, Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor
Authors:Willcox, B.E, Thomas, L.M, Chapman, T.L, Heikema, A.P, West, A.P, Bjorkman, P.J.
Deposit date:2006-05-03
Release date:2006-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.
Bmc Struct.Biol., 2, 2002
4JDT
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BU of 4jdt by Molmil
Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Scharf, L, Diskin, R, Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JKP
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BU of 4jkp by Molmil
Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2013-03-11
Release date:2013-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
J.Exp.Med., 210, 2013
4JDV
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BU of 4jdv by Molmil
Crystal structure of germ-line precursor of NIH45-46 Fab
Descriptor: Fab heavy chain, Fab light chain, GLYCEROL, ...
Authors:Diskin, R, Scharf, L, Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
7U0C
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BU of 7u0c by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.4
Descriptor: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2022-02-17
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7U0B
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BU of 7u0b by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.1
Descriptor: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2022-02-17
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
Descriptor: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2022-01-26
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
7UCE
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BU of 7uce by Molmil
Structure of the anti-HIV-1 neutralizing antibody BG24 Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG24 Fab heavy chain, BG24 Fab light chain
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-16
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCG
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BU of 7ucg by Molmil
Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
Descriptor: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-16
Release date:2022-08-17
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCF
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BU of 7ucf by Molmil
Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-16
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4 Å)
Cite:A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGN
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BU of 7ugn by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
Descriptor: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UZA
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BU of 7uza by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-1 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ7
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BU of 7uz7 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-31 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ5
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BU of 7uz5 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-6 Fab heavy chain, M8a-6 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ4
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BU of 7uz4 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-3 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022

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数据于2024-06-12公开中

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