7RYU
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Summary for 7RYU
Entry DOI | 10.2210/pdb7ryu/pdb |
Descriptor | Ab1303 Fab heavy chain, Ab1303 Fab light chain (3 entities in total) |
Functional Keywords | anti-hiv neutralizing antibody; antibody fab;, immune system |
Biological source | Macaca mulatta (Rhesus monkey) More |
Total number of polymer chains | 2 |
Total formula weight | 48758.15 |
Authors | Yang, Z.,Bjorkman, P.J. (deposition date: 2021-08-26, release date: 2022-01-19, Last modification date: 2023-10-18) |
Primary citation | Yang, Z.,Dam, K.A.,Bridges, M.D.,Hoffmann, M.A.G.,DeLaitsch, A.T.,Gristick, H.B.,Escolano, A.,Gautam, R.,Martin, M.A.,Nussenzweig, M.C.,Hubbell, W.L.,Bjorkman, P.J. Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13:732-732, 2022 Cited by PubMed: 35136084DOI: 10.1038/s41467-022-28424-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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