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7UZ5

Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6

Summary for 7UZ5
Entry DOI10.2210/pdb7uz5/pdb
EMDB information26879
DescriptorSpike glycoprotein, M8a-6 Fab heavy chain, M8a-6 Fab light chain, ... (4 entities in total)
Functional Keywordsimmune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
More
Total number of polymer chains5
Total formula weight477529.67
Authors
Fan, C.,Bjorkman, P.J. (deposition date: 2022-05-08, release date: 2022-12-07, Last modification date: 2022-12-28)
Primary citationFan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J.
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55:2419-, 2022
Cited by
PubMed: 36370711
DOI: 10.1016/j.immuni.2022.10.019
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

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