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5VJN
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BU of 5vjn by Molmil
Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with D-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (D-DIAB) and Adenine
Descriptor: 1,2-ETHANEDIOL, ADENINE, Adenine phosphoribosyltransferase 1, ...
Authors:Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L.
Deposit date:2017-04-19
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.
ACS Chem. Biol., 13, 2018
5VJP
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Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with L-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (L-DIAB) and Adenine
Descriptor: 1,2-ETHANEDIOL, ADENINE, Adenine phosphoribosyltransferase 1, ...
Authors:Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L.
Deposit date:2017-04-19
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.
ACS Chem. Biol., 13, 2018
1B8O
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PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Fedorov, A.A, Kicska, G.A, Fedorov, E.V, Shi, W, Tyler, P.C, Furneaux, R.H, Schramm, V.L, Almo, S.C.
Deposit date:1999-02-02
Release date:1999-02-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Biochemistry, 40, 2001
1Y6Q
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Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, MTA/SAH nucleosidase
Authors:Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L.
Deposit date:2004-12-06
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
J.Biol.Chem., 280, 2005
1DQP
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CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING
Descriptor: 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL
Authors:Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:2000-01-04
Release date:2000-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
1DQN
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CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
Descriptor: GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:2000-01-04
Release date:2000-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
1EZR
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BU of 1ezr by Molmil
CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR
Descriptor: CALCIUM ION, NUCLEOSIDE HYDROLASE
Authors:Shi, W, Schramm, V.L, Almo, S.C.
Deposit date:2000-05-11
Release date:2000-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem., 274, 1999
7RXV
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BU of 7rxv by Molmil
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine, Malonate (MLA) and MgF3
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, ALANINE, GLYCEROL, ...
Authors:Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
Deposit date:2021-08-23
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
7RXW
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BU of 7rxw by Molmil
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor imido-diphosphate (PNP)
Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ALANINE, ...
Authors:Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
Deposit date:2021-08-23
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
7RXX
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Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and two sulfate in the active site
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ...
Authors:Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
Deposit date:2021-08-23
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
1B8N
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BU of 1b8n by Molmil
PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor: 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Fedorov, A.A, Kicska, G.A, Fedorov, E.V, Strokopytov, B.V, Tyler, P.C, Furneaux, R.H, Schramm, V.L, Almo, S.C.
Deposit date:1999-02-02
Release date:1999-02-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
Biochemistry, 41, 2002
1BZY
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BU of 1bzy by Molmil
HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR
Descriptor: HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ...
Authors:Shi, W, Li, C, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:1998-11-05
Release date:1999-06-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
Nat.Struct.Biol., 6, 1999
1CJB
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BU of 1cjb by Molmil
MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE
Descriptor: (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE, MAGNESIUM ION, PROTEIN (HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE), ...
Authors:Shi, W, Li, C.M, Tyler, P.C, Furneaux, R.H, Cahill, S.M, Girvin, M.E, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:1999-04-08
Release date:1999-08-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Biochemistry, 38, 1999
2Q7O
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Structure of human purine nucleoside phosphorylase in complex with L-Immucillin-H
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
Deposit date:2007-06-07
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
J.Am.Chem.Soc., 130, 2008
2P4S
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BU of 2p4s by Molmil
Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH
Descriptor: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
Deposit date:2007-03-13
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Biochemistry, 46, 2007
2ON6
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BU of 2on6 by Molmil
Crystal structure of human purine nucleoside phosphorylase mutant H257F with Imm-H
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, Purine nucleoside phosphorylase
Authors:Rinaldo-Matthis, A, Murkin, A.S, Almo, S.C, Schramm, V.L.
Deposit date:2007-01-23
Release date:2007-05-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase
Biochemistry, 46, 2007
2OC9
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BU of 2oc9 by Molmil
Crystal structure of human purine nucleoside phosphorylase mutant H257G with Imm-H
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
Deposit date:2006-12-20
Release date:2007-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase
Biochemistry, 46, 2007
2OC4
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Crystal structure of human purine nucleoside phosphorylase mutant H257D with Imm-H
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
Deposit date:2006-12-20
Release date:2007-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase
Biochemistry, 46, 2007
1G2P
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CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE
Descriptor: ADENINE PHOSPHORIBOSYLTRANSFERASE 1, SULFATE ION
Authors:Shi, W, Tanaka, K.S.E, Almo, S.C, Schramm, V.L.
Deposit date:2000-10-20
Release date:2001-12-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry, 40, 2001
1G2O
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CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR
Descriptor: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
Authors:Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L.
Deposit date:2000-10-20
Release date:2001-08-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
1I80
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BU of 1i80 by Molmil
CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION
Descriptor: 9-DEAZAHYPOXANTHINE, IMINORIBITOL, PHOSPHATE ION, ...
Authors:Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L.
Deposit date:2001-03-12
Release date:2001-08-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
1G2Q
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CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE
Descriptor: ADENINE PHOSPHORIBOSYLTRANSFERASE 1
Authors:Shi, W, Tanaka, K.S.E, Almo, S.C, Schramm, V.L.
Deposit date:2000-10-20
Release date:2001-12-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry, 40, 2001
4UC0
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BU of 4uc0 by Molmil
Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
Descriptor: HYPOXANTHINE, Purine nucleoside phosphorylase
Authors:Cameron, S.A, Sampathkumar, P, Ramagopal, U.A, Attonito, J, Ahmed, M, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Schramm, V.L, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-08-13
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
To be published
1ZOS
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BU of 1zos by Molmil
Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA
Descriptor: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
Authors:Shi, W, Singh, V, Zhen, R, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L.
Deposit date:2005-05-13
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Biochemistry, 45, 2006
3LOO
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BU of 3loo by Molmil
Crystal structure of Anopheles gambiae adenosine kinase in complex with P1,P4-di(adenosine-5) tetraphosphate
Descriptor: Anopheles gambiae adenosine kinase, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CHLORIDE ION, ...
Authors:Ho, M.-C, Cassera, M.B, Almo, S.C, Schramm, V.L.
Deposit date:2010-02-04
Release date:2011-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:A High-Affinity Adenosine Kinase from Anopheles gambiae.
Biochemistry, 50, 2011

221716

数据于2024-06-26公开中

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