2P4S

Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH

Summary for 2P4S

• Entry DOI: 10.2210/pdb2p4s/pdb
• Descriptor: Purine nucleoside phosphorylase, PHOSPHATE ION, 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, ... (4 entities in total)
• Functional Keywords: purine nucleoside phosphorylase, transferase
• Biological source: Anopheles gambiae (African malaria mosquito)
• Total number of polymer chains: 3
• Total formula weight: 124102.35

Authors

Rinaldo-Matthis, A.,Almo, S.C.,Schramm, V.L. (deposition date: 2007-03-13, release date: 2008-01-15, Last modification date: 2023-08-30)

• Primary citation: Taylor, E.A.,Rinaldo-Matthis, A.,Li, L.,Ghanem, M.,Hazleton, K.Z.,Cassera, M.B.,Almo, S.C.,Schramm, V.L.; Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.; Biochemistry, 46:12405-12415, 2007; PubMed: 17918964; DOI: 10.1021/bi7010256

Experimental method

X-RAY DIFFRACTION (2.2 Å)