2P4S

Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Purine nucleoside phosphorylase	polymer	373	40975.5	3	UniProt (A4Q998) Pfam (PF01048) In PDB	Anopheles gambiae (African malaria mosquito)
2	A, B, C	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
3	A, B, C	7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one	non-polymer		265.3	3	Chemie (DIH)
4		water	water		18.0	363	Chemie (HOH)

Sequence modifications

A, B, C: 21 - 373 (UniProt: A4Q998)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	122926.6
Non-Polymers*	Number of molecules	7
	Total formula weight	1175.7
All*	Total formula weight	124102.4

*Water molecules are not included.