2OC4
Crystal structure of human purine nucleoside phosphorylase mutant H257D with Imm-H
Summary for 2OC4
Entry DOI | 10.2210/pdb2oc4/pdb |
Related | 2A0W 2A0X 2A0Y 2OC9 2ON6 |
Descriptor | Purine nucleoside phosphorylase, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton : P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32523.04 |
Authors | Rinaldo-Matthis, A.,Almo, S.C.,Schramm, V.L. (deposition date: 2006-12-20, release date: 2007-05-22, Last modification date: 2023-09-20) |
Primary citation | Murkin, A.S.,Birck, M.R.,Rinaldo-Matthis, A.,Shi, W.,Taylor, E.A.,Almo, S.C.,Schramm, V.L. Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46:5038-5049, 2007 Cited by PubMed: 17407325DOI: 10.1021/bi700147b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.592 Å) |
Structure validation
Download full validation report