2OC4
Crystal structure of human purine nucleoside phosphorylase mutant H257D with Imm-H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Purine nucleoside phosphorylase | polymer | 289 | 32161.8 | 1 | UniProt (P00491) Pfam (PF01048) | Homo sapiens (human) | Inosine phosphorylase; PNP |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL | non-polymer | 266.3 | 1 | Chemie (IMH) | |||
| 4 | D (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: P00491)
| PDB | External Database | Details |
|---|---|---|
| Ser 51 | Gly 51 | engineered mutation |
| Asp 257 | His 257 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32161.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 361.2 | |
| All* | Total formula weight | 32523.0 |
