2Q7O
Structure of human purine nucleoside phosphorylase in complex with L-Immucillin-H
Summary for 2Q7O
Entry DOI | 10.2210/pdb2q7o/pdb |
Related | 1rr6 |
Descriptor | Purine nucleoside phosphorylase, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton : P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32546.10 |
Authors | Rinaldo-Matthis, A.,Almo, S.C.,Schramm, V.L. (deposition date: 2007-06-07, release date: 2008-01-15, Last modification date: 2023-08-30) |
Primary citation | Rinaldo-Matthis, A.,Murkin, A.S.,Ramagopal, U.A.,Clinch, K.,Mee, S.P.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase. J.Am.Chem.Soc., 130:842-844, 2008 Cited by PubMed: 18154341DOI: 10.1021/ja710733g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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