2ON6

Crystal structure of human purine nucleoside phosphorylase mutant H257F with Imm-H

Summary for 2ON6

Entry DOI	10.2210/pdb2on6/pdb
Related	2A0W 2A0X 2A0Y 2OC4 2OC9
Descriptor	Purine nucleoside phosphorylase, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL (3 entities in total)
Functional Keywords	purine nucleoside phosphorylase, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton : P00491
Total number of polymer chains	1
Total formula weight	32460.16
Authors	Rinaldo-Matthis, A.,Murkin, A.S.,Almo, S.C.,Schramm, V.L. (deposition date: 2007-01-23, release date: 2007-05-22, Last modification date: 2022-10-05)
Primary citation	Murkin, A.S.,Birck, M.R.,Rinaldo-Matthis, A.,Shi, W.,Taylor, E.A.,Almo, S.C.,Schramm, V.L. Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46:5038-5049, 2007 Cited by PubMed: 17407325 DOI: 10.1021/bi700147b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.503 Å)

Structure validation