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3LTH
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BU of 3lth by Molmil
E. cloacae MurA dead-end complex with UNAG and fosfomycin
Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, [(1R)-1-hydroxypropyl]phosphonic acid
Authors:Schonbrunn, E.
Deposit date:2010-02-15
Release date:2010-05-05
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Biochemistry, 49, 2010
3FK1
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BU of 3fk1 by Molmil
E. coli EPSP synthase (TIPS mutation) liganded with S3P and glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, N-(phosphonomethyl)glycine, ...
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FJX
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BU of 3fjx by Molmil
E. coli EPSP synthase (T97I) liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FJZ
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BU of 3fjz by Molmil
E. coli EPSP synthase (T97I) liganded with S3P and glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, N-(phosphonomethyl)glycine, ...
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FK0
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BU of 3fk0 by Molmil
E. coli EPSP synthase (TIPS mutation) liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
8G6T
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BU of 8g6t by Molmil
Bromodomain of CBP liganded with inhibitor iCBP2
Descriptor: (6S)-1-(3,4-dibromophenyl)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one, CREB-binding protein, NICKEL (II) ION
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-02-15
Release date:2024-02-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FVS
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BU of 8fvs by Molmil
Bromodomain of CBP liganded with CCS1477int
Descriptor: 1,2-ETHANEDIOL, Histone acetyltransferase, MAGNESIUM ION, ...
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-19
Release date:2024-01-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FV2
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BU of 8fv2 by Molmil
Bromodomain of CBP liganded with CCS-1477
Descriptor: (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein, ...
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-18
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FVF
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BU of 8fvf by Molmil
Bromodomain of EP300 liganded with CCS-1477
Descriptor: (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, 1,2-ETHANEDIOL, Histone acetyltransferase p300, ...
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-18
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FXE
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BU of 8fxe by Molmil
Bromodomain of CBP liganded with iCBP6
Descriptor: (6S)-1-(3-tert-butylphenyl)-6-{(5P)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-24
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FVK
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BU of 8fvk by Molmil
First bromodomain of BRD4 liganded with CCS-1477
Descriptor: (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-19
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FXA
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BU of 8fxa by Molmil
Bromodomain of CBP liganded with iCBP4
Descriptor: (6S)-1-[3,5-bis(trifluoromethyl)phenyl]-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-24
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8FXO
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BU of 8fxo by Molmil
Bromodomain of CBP liganded with iCBP8
Descriptor: (6S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one, CREB-binding protein
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-01-25
Release date:2024-02-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
8GA2
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BU of 8ga2 by Molmil
Bromodomain of CBP liganded with inhibitor iCBP5
Descriptor: (6S)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}-1-phenylpiperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein
Authors:Schonbrunn, E, Bikowitz, M.
Deposit date:2023-02-22
Release date:2024-02-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun, 15, 2024
3KQA
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BU of 3kqa by Molmil
MurA dead-end complex with terreic acid
Descriptor: (5S)-2,5-dihydroxy-3-methylcyclohex-2-ene-1,4-dione, CALCIUM ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Authors:Schonbrunn, E.
Deposit date:2009-11-17
Release date:2010-04-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Biochemistry, 49, 2010
3KR6
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BU of 3kr6 by Molmil
MurA dead-end complex with fosfomycin
Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, [(1R)-1-hydroxypropyl]phosphonic acid
Authors:Schonbrunn, E.
Deposit date:2009-11-17
Release date:2010-04-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Biochemistry, 49, 2010
3KQJ
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BU of 3kqj by Molmil
MurA binary complex with UDP-N-acetylglucosamine
Descriptor: GLYCEROL, PHOSPHATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ...
Authors:Schonbrunn, E.
Deposit date:2009-11-17
Release date:2010-04-28
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Natural Product Antibiotic Terreic Acid is a Mechanism-Based Inhibitor of the Bacterial Enzyme MurA in vitro but not in vivo.
To be Published
2GGA
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BU of 2gga by Molmil
CP4 EPSP synthase liganded with S3P and Glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E, Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GG6
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BU of 2gg6 by Molmil
CP4 EPSP synthase liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, SULFATE ION
Authors:Schonbrunn, E, Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GGD
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BU of 2ggd by Molmil
CP4 EPSP synthase Ala100Gly liganded with S3P and Glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E, Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GG4
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BU of 2gg4 by Molmil
CP4 EPSP synthase (unliganded)
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase
Authors:Schonbrunn, E, Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3ELL
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BU of 3ell by Molmil
Structure of the hemophore from Pseudomonas aeruginosa (HasAp)
Descriptor: HasAp (Heme acquisition protein HasAp), PROTOPORPHYRIN IX CONTAINING FE
Authors:Schonbrunn, E, Rivera, M.
Deposit date:2008-09-22
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between Holo-HasAp and hemoglobin.
Biochemistry, 48, 2009
2QFQ
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BU of 2qfq by Molmil
E. coli EPSP synthase Pro101Leu liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E, Healy-Fried, M.L.
Deposit date:2007-06-27
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QFT
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BU of 2qft by Molmil
E.coli EPSP synthase Pro101Ser liganded with S3P and glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, GLYPHOSATE, ...
Authors:Schonbrunn, E, Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QFS
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BU of 2qfs by Molmil
E.coli EPSP synthase Pro101Ser liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E, Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007

239149

数据于2025-07-23公开中

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