3KQJ

MurA binary complex with UDP-N-acetylglucosamine

Summary for 3KQJ

Related3KQA 3KR6
DescriptorUDP-N-acetylglucosamine 1-carboxyvinyltransferase, GLYCEROL, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... (5 entities in total)
Functional Keywordsclosed enzyme state, inside-out alpha/beta barrel, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, peptidoglycan synthesis, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Probable) P0A749
Total number of polymer chains1
Total molecular weight45666.94
Authors
Schonbrunn, E. (deposition date: 2009-11-17, release date: 2010-04-28, Last modification date: 2011-07-27)
Primary citation
Han, H.,Yang, Y.,Olesen, S.H.,Becker, A.,Betzi, S.,Schonbrunn, E.
The Natural Product Antibiotic Terreic Acid is a Mechanism-Based Inhibitor of the Bacterial Enzyme MurA in vitro but not in vivo.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.194701.2%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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