3KQJ
MurA binary complex with UDP-N-acetylglucosamine
Summary for 3KQJ
| Entry DOI | 10.2210/pdb3kqj/pdb |
| Related | 3KQA 3KR6 |
| Descriptor | UDP-N-acetylglucosamine 1-carboxyvinyltransferase, GLYCEROL, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... (5 entities in total) |
| Functional Keywords | closed enzyme state, inside-out alpha/beta barrel, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, peptidoglycan synthesis, transferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm (Probable): P0A749 |
| Total number of polymer chains | 1 |
| Total formula weight | 45666.94 |
| Authors | Schonbrunn, E. (deposition date: 2009-11-17, release date: 2010-04-28, Last modification date: 2024-11-27) |
| Primary citation | Han, H.,Yang, Y.,Olesen, S.H.,Becker, A.,Betzi, S.,Schonbrunn, E. The Natural Product Antibiotic Terreic Acid is a Mechanism-Based Inhibitor of the Bacterial Enzyme MurA in vitro but not in vivo. To be Published, |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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