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3KQJ

MurA binary complex with UDP-N-acetylglucosamine

Summary for 3KQJ
Entry DOI10.2210/pdb3kqj/pdb
Related3KQA 3KR6
DescriptorUDP-N-acetylglucosamine 1-carboxyvinyltransferase, GLYCEROL, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... (5 entities in total)
Functional Keywordsclosed enzyme state, inside-out alpha/beta barrel, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, peptidoglycan synthesis, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Probable): P0A749
Total number of polymer chains1
Total formula weight45666.94
Authors
Schonbrunn, E. (deposition date: 2009-11-17, release date: 2010-04-28, Last modification date: 2023-09-06)
Primary citationHan, H.,Yang, Y.,Olesen, S.H.,Becker, A.,Betzi, S.,Schonbrunn, E.
The Natural Product Antibiotic Terreic Acid is a Mechanism-Based Inhibitor of the Bacterial Enzyme MurA in vitro but not in vivo.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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