E. coli EPSP synthase (TIPS mutation) liganded with S3P

Summary for 3FK0

Related1g6t 2qfs 2qft 3FJX 3FJZ 3FK1
Descriptor3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID, ... (4 entities in total)
Functional Keywordsinside-out alpha-beta barrel, amino-acid biosynthesis, aromatic amino acid biosynthesis, cytoplasm, transferase
Biological sourceEscherichia coli K-12
Cellular locationCytoplasm  P0A6D3
Total number of polymer chains1
Total molecular weight46811.99
Schonbrunn, E. (deposition date: 2008-12-15, release date: 2009-02-17, Last modification date: 2018-01-24)
Primary citation
Funke, T.,Yang, Y.,Han, H.,Healy-Fried, M.,Olesen, S.,Becker, A.,Schonbrunn, E.
Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284:9854-9860, 2009
PubMed: 19211556 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M809771200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.204501.2%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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