E. coli EPSP synthase (T97I) liganded with S3P and glyphosate

Summary for 3FJZ

Related1g6t 2qft 3FJX 3FK0 3FK1
Descriptor3-phosphoshikimate 1-carboxyvinyltransferase, SERINE, N-(phosphonomethyl)glycine, ... (6 entities in total)
Functional Keywordsinside-out alpha-beta barrel, amino-acid biosynthesis, aromatic amino acid biosynthesis, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Probable) P0A6D3
Total number of polymer chains1
Total molecular weight47050.16
Schonbrunn, E. (deposition date: 2008-12-15, release date: 2009-02-17, Last modification date: 2012-02-29)
Primary citation
Funke, T.,Yang, Y.,Han, H.,Healy-Fried, M.,Olesen, S.,Becker, A.,Schonbrunn, E.
Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284:9854-9860, 2009
PubMed: 19211556 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M809771200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.178301.2%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16