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5W7V
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BU of 5w7v by Molmil
CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Ge, P, Eisenberg, D.S.
Deposit date:2017-06-20
Release date:2018-03-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WHP
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BU of 5whp by Molmil
Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317
Descriptor: Segment of TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-17
Release date:2018-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WIQ
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BU of 5wiq by Molmil
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-19
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5W50
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BU of 5w50 by Molmil
Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-06-13
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WHN
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BU of 5whn by Molmil
Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317
Descriptor: Segment of TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-17
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
1LNX
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BU of 1lnx by Molmil
Crystal structure of the P.aerophilum SmAP1 heptamer in a new crystal form (C2221)
Descriptor: ACETIC ACID, GLYCEROL, URIDINE, ...
Authors:Mura, C, Kozhukhovsky, A, Eisenberg, D.
Deposit date:2002-05-04
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
1LOJ
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BU of 1loj by Molmil
Crystal structure of a Methanobacterial Sm-like archaeal protein (SmAP1) bound to uridine-5'-monophosphate (UMP)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, URIDINE, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Mura, C, Kozhukhovsky, A, Eisenberg, D.
Deposit date:2002-05-06
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
3NHD
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BU of 3nhd by Molmil
GYVLGS segment 127-132 from human prion with V129
Descriptor: ACETIC ACID, Major prion protein
Authors:Apostol, M.I, Eisenberg, D.
Deposit date:2010-06-14
Release date:2010-08-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
3NVE
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BU of 3nve by Molmil
MMHFGN segment 138-143 from Syrian Hamster prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVF
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BU of 3nvf by Molmil
IIHFGS segment 138-143 from human prion
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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BU of 3nvg by Molmil
MIHFGN segment 137-142 from mouse prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
4I0X
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BU of 4i0x by Molmil
Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex
Descriptor: BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ...
Authors:Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-11-19
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
3NHC
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BU of 3nhc by Molmil
GYMLGS segment 127-132 from human prion with M129
Descriptor: Major prion protein
Authors:Apostol, M.I, Eisenberg, D.
Deposit date:2010-06-14
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
3NVH
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BU of 3nvh by Molmil
MIHFGND segment 137-143 from mouse prion
Descriptor: Major prion protein, trifluoroacetic acid
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3L2L
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BU of 3l2l by Molmil
X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Limit Dextrin and Oligosaccharide
Descriptor: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ...
Authors:Larson, S.B, Day, J.S, McPherson, A.
Deposit date:2009-12-15
Release date:2010-04-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
Biochemistry, 49, 2010
3L2M
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BU of 3l2m by Molmil
X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Alpha-cyclodextrin
Descriptor: CALCIUM ION, CHLORIDE ION, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ...
Authors:Larson, S.B, Day, J.S, McPherson, A.
Deposit date:2009-12-15
Release date:2010-04-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
Biochemistry, 49, 2010
6CF4
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BU of 6cf4 by Molmil
Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317
Descriptor: NFGTFS
Authors:Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-13
Release date:2018-05-23
Last modified:2021-06-30
Method:ELECTRON CRYSTALLOGRAPHY (0.75 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5KMZ
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BU of 5kmz by Molmil
Solution NMR structure of Tetrahymena telomerase RNA pseudoknot
Descriptor: Telomerase RNA pseudoknot
Authors:Cash, D.D, Feigon, J.
Deposit date:2016-06-27
Release date:2016-10-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
1RHG
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BU of 1rhg by Molmil
THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS
Descriptor: GRANULOCYTE COLONY-STIMULATING FACTOR
Authors:Hill, C.P, Osslund, T.D, Eisenberg, D.
Deposit date:1993-01-29
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors.
Proc.Natl.Acad.Sci.USA, 90, 1993
6AXZ
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BU of 6axz by Molmil
Segment from bank vole prion protein 168-176 QYNNQNNFV
Descriptor: Major prion protein
Authors:Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M.
Deposit date:2017-09-07
Release date:2018-01-17
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (0.75 Å)
Cite:Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.
Nat. Struct. Mol. Biol., 25, 2018
6BTK
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BU of 6btk by Molmil
Segment from bank vole prion protein 168-176 QYNNQNNFV
Descriptor: Major prion protein
Authors:Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M.
Deposit date:2017-12-06
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.
Nat. Struct. Mol. Biol., 25, 2018
6CFH
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BU of 6cfh by Molmil
SWGMMGMLASQ segment from the low complexity domain of TDP-43
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-15
Release date:2018-05-23
Last modified:2024-05-15
Method:ELECTRON CRYSTALLOGRAPHY (1.5 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5CY5
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BU of 5cy5 by Molmil
Crystal structure of the T33-51H designed self-assembling protein tetrahedron
Descriptor: T33-51H-A, T33-51H-B
Authors:Cannon, K.A, Cascio, D, Park, R, Boyken, S, King, N, Yeates, T.O.
Deposit date:2015-07-30
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
6CB9
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BU of 6cb9 by Molmil
Segment AALQSS from the low complexity domain of TDP-43, residues 328-333
Descriptor: AALQSS
Authors:Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-02
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CEW
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BU of 6cew by Molmil
Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326
Descriptor: AMMAAA
Authors:Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-12
Release date:2018-04-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018

224004

数据于2024-08-21公开中

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