6CEW

Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326

Summary for 6CEW

• Entry DOI: 10.2210/pdb6cew/pdb
• Related: 6CB9
• Descriptor: AMMAAA (2 entities in total)
• Functional Keywords: amyloid, steric-zipper, protein fibril
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 1129.44

Authors

Guenther, E.L.,Cao, Q.,Lu, J.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-02-12, release date: 2018-04-18, Last modification date: 2024-04-03)

• Primary citation: Guenther, E.L.,Cao, Q.,Trinh, H.,Lu, J.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Rodriguez, J.A.,Hughes, M.P.,Eisenberg, D.S.; Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.; Nat. Struct. Mol. Biol., 25:463-471, 2018; PubMed: 29786080; DOI: 10.1038/s41594-018-0064-2

Experimental method

X-RAY DIFFRACTION (1.2 Å)