3NVF
IIHFGS segment 138-143 from human prion
Summary for 3NVF
| Entry DOI | 10.2210/pdb3nvf/pdb |
| Related | 3NVE 3NVG 3NVH |
| Descriptor | Major prion protein, (4S)-2-METHYL-2,4-PENTANEDIOL (2 entities in total) |
| Functional Keywords | amyloid-like protofibril, protein fibril |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
| Total number of polymer chains | 1 |
| Total formula weight | 791.95 |
| Authors | Apostol, M.I.,Sawaya, M.R.,Eisenberg, D. (deposition date: 2010-07-08, release date: 2011-03-02, Last modification date: 2024-02-21) |
| Primary citation | Apostol, M.I.,Wiltzius, J.J.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. Atomic structures suggest determinants of transmission barriers in Mammalian prion disease. Biochemistry, 50:2456-2463, 2011 Cited by PubMed: 21323366DOI: 10.1021/bi101803k PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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