6CFH

SWGMMGMLASQ segment from the low complexity domain of TDP-43

Summary for 6CFH

Entry DOI	10.2210/pdb6cfh/pdb
Related	6cb9 6cew 6cf4
EMDB information	7467
Descriptor	TAR DNA-binding protein 43 (1 entity in total)
Functional Keywords	amyloid, steric zipper, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	2396.87
Authors	Guenther, E.L.,Rodriguez, J.A.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-02-15, release date: 2018-05-23, Last modification date: 2021-10-13)
Primary citation	Guenther, E.L.,Cao, Q.,Trinh, H.,Lu, J.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Rodriguez, J.A.,Hughes, M.P.,Eisenberg, D.S. Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25:463-471, 2018 Cited by PubMed: 29786080 DOI: 10.1038/s41594-018-0064-2 PDB entries with the same primary citation
Experimental method	ELECTRON CRYSTALLOGRAPHY (1.5 Å)

Structure validation