5W50
Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253
Summary for 5W50
| Entry DOI | 10.2210/pdb5w50/pdb |
| Descriptor | TAR DNA-binding protein 43 (2 entities in total) |
| Functional Keywords | amyloid, steric zipper, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 1313.76 |
| Authors | Guenther, E.L.,Trinh, H.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2017-06-13, release date: 2018-02-21, Last modification date: 2023-10-04) |
| Primary citation | Guenther, E.L.,Ge, P.,Trinh, H.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Gonen, T.,Zhou, Z.H.,Eisenberg, D.S. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25:311-319, 2018 Cited by PubMed: 29531287DOI: 10.1038/s41594-018-0045-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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